Results 51 to 60 of about 260,075 (296)

Determinants of Outcome with Reoperative Surgery for Pseudomyxoma Peritonei in 186 Patients

open access: yesAnnals of Surgery Open, 2023
Objective:. To describe the long-term survival and clinical- and treatment-related variables that determine the outcome of repeat cytoreductive surgery (CRS) for mucinous appendiceal neoplasms with peritoneal dissemination. Summary Background:.
Paul H. Sugarbaker, MD, David Chang, MS
doaj   +1 more source

A STUDY OF RETRO-PERITONEAL NEOPLASMS WITH SPECIAL REFERENCE TO DIAGNOSIS. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1898
Definition. —For the purpose of my paper I accept the limitation suggested by Mr. Lockwood for retro-peritoneal neoplasms. The term implies a solid or cystic tumor growing behind the peritoneum, into its folds and not connected with any of the great retro-peritoneal organs. So we at once eliminate from our consideration tumors of the kidneys, pancreas,
openaire   +2 more sources

Effects of spironolactone on residual renal function and peritoneal function in peritoneal dialysis patients

open access: yes, 2021
There is increasing evidence that long-term peritoneal dialysis (PD) is associated with structural changes in the peritoneal membrane. Inhibition of the renin-angiotensin system has been demonstrated to lessen peritoneal injury and to slow the decline in
Ozturk, Savaş   +9 more
core  

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

open access: yesAdvanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li   +14 more
wiley   +1 more source

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

open access: yesAdvanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao   +9 more
wiley   +1 more source

Old and new perspectives on peritoneal dialysis in Italy emerging from the Peritoneal Dialysis Study Group Census.

open access: yes, 2012
Background: To understand how peritoneal dialysis (PD) was being used in Italy in 2005 and 2008, a census of all centers was carried out. Methods: In 2005 and 2008, data were collected from, respectively, 222 and 223 centers, with respect to 4432 and ...
Teatini U   +7 more
core   +1 more source

Eye‐Brain Neuroimmune Axis Enables Long‐Term Survival in Glioblastoma by Modulating Brain Immune Surveillance and Neuronal Excitability

open access: yesAdvanced Science, EarlyView.
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui   +9 more
wiley   +1 more source

Peritoneal metastatic mixed adenoneuroendocrine carcinoma treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a case report [PDF]

open access: yesAnnals of Coloproctology
A 61-year-old man presented with abdominal distension without any symptoms. On colonoscopy and computed tomography findings, it was clinically diagnosed as peritoneal metastasis of sigmoid colon cancer, and diagnostic laparoscopy was performed.
Sungchul Lee, Euitae Kim, Dong-Guk Park
doaj   +1 more source

Clinical outcome in continuous ambulatory peritoneal dialysis patients is not influenced by high peritoneal transport status [PDF]

open access: yes, 2001
OBJECTIVES: We undertook this study to examine the influence of demographics, peritoneal membrane transport characteristics, nutrition indices, dialysis adequacy, and comorbid diseases on patient survival on continuous ambulatory peritoneal dialysis ...
박형천, 최규헌
core  

Functional Suppression of SCAP Triggers Endoplasmic Reticulum Stress‐Dependent Ferroptosis by Impairing Cholesterol Metabolism in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu   +17 more
wiley   +1 more source

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