Results 41 to 50 of about 108,249 (257)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Large falciform ligament cyst in a child: A rare entity of peritoneal cysts and review of the literature

open access: yesAfrican Journal of Paediatric Surgery, 2020
Peritoneal cysts are not uncommon in children – mesenteric/omental cysts being the commoner entity. Peritoneal cysts in the falciform ligament are a very rare entity reported in the literature.
Enono Yhoshu   +3 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Effects of Boric Acid on Ehrlich Ascites Tumor

open access: yesİstanbul Medical Journal, 2018
Introduction: Cancer is one of the most important healthcare problems in the world. Boric acid has cytotoxic activity, but there is insufficient data on its effectiveness for cancer development.
Ufuk Oğuz İdiz   +4 more
doaj   +1 more source

Cutaneous melanoma in older patients

open access: yesBMC Geriatrics
Background In industrialized countries, the aging population is steadily rising. The incidence of cutaneous malignant melanoma (CMM) is highest in old people.
Alessandra Buja   +11 more
doaj   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

open access: yesAdvanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong   +4 more
wiley   +1 more source

Diagnostic challenges and importance of early multidisciplinary intervention in acral melanoma: a case report

open access: yesDermatology Reports
Acral melanoma (AM) is a rare subtype of melanoma that occurs on acral sites such as the palms, soles, and subungual regions. Due to its atypical presentation and frequent lack of pigmentation in the amelanotic variant (AAM), diagnosis is often delayed ...
Fortunato Cassalia   +5 more
doaj   +1 more source

The Diagnostic Usefulness of Ultrasound-Guided Peritoneal Biopsy for the Solitary Peritoneal Thickening of an Unknown Cause Visualized as Only Infiltrated Fat Tissue on a CT Scan

open access: yes대한영상의학회지, 2018
Purpose: To assess the usefulness of an ultrasound (US)-guided peritoneal biopsy for the solitary peritoneal thickening visualized as only infiltrated fat on a computed tomography (CT) scan.
Yun Ju Chu   +7 more
doaj   +1 more source

Surgical repair of giant inguinoscrotal hernia containing the urinary bladder

open access: yesMedical Journal of Dr. D.Y. Patil University, 2013
Inguinal hernia repair is one of the commonest operations in surgical practice. Unusual contents of hernia sac are uncommon, but are likely to be encountered by a surgeon in his career due to the frequency of hernia repair.
Suryapratap Singh Tomar   +1 more
doaj   +1 more source

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