Mineralization of the Peritoneum — a New Target in the Treatment of Peritoneal Carcinomatosis
Креативная хирургия и онкология, 2019 Introduction. This article presents data on the manifestations of changes in the microenvironment of the peritoneal cavity in patients with carcinomatosis, expressed by the mineralization of the peritoneum, which in turn leads to functional changes in ...
Sh. Kh. Gantsev +7 more
doaj +1 more source
LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome [PDF]
, 2013 Natural variation for LPS-induced lethal inflammation in mice is useful for identifying new genes that regulate sepsis, which could form the basis for novel therapies for systemic inflammation in humans.
Beaulieu E +12 more
core +2 more sources
Advanced Science, EarlyView.Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang +16 more
wiley +1 more source
DIFFERENTIAL DIAGNOSIS OF ACUTE INTESTINAL INFECTIONS OF SURGICAL AND ONCOLOGICAL DISEASES
Креативная хирургия и онкология, 2017 Presents an analysis of outpatient and inpatient medical records of patients delivered in infectious hospital № 4 of Ufa with suspected acute intestinal infection and transferred after clinical laboratory examination or from admissions for emergency ...
D. A. Valishin +5 more
doaj +1 more source
72 Can intraoperative visual examination of diaphragmatic peritoneum be a reliable tool to modulate the extent of interval debulking surgery in advanced ovarian cancer? [PDF]
, 2020 Virginia Vargiu +5 more
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Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections
Advanced Science, EarlyView.This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin +3 more
wiley +1 more source
Креативная хирургия и онкология, 2017 This article describes the results of scanning electron microscopy in cancer. For the first time visualized the cancer cells migrated via directly serous-lymphatic hatches on the surface peritoneum.
Sh. Kh. Gantsev +5 more
doaj +1 more source
ORGAN SPECIFIC VASCULAR RESPONSE TO FIBROSIS AFFECTS BREAST CANCER METASTATIC ORGANOTROPISM [PDF]
, 2016 The solid tumor microenvironment, pre-metastatic niche, and fibrotic environment are known to have significant biochemical and biomechanical similarities to the fibrotic environment. All have significantly increased levels of factors such as TGFβ, HIF1α,
Fletcher, Eliot S, Fletcher, Eliot S
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Genomic profiling of malignant peritoneal mesothelioma reveals recurrent alterations in epigenetic regulatory genes BAP1, SETD2, and DDX3X. [PDF]
, 2017 Malignant mesothelioma is a rare cancer that arises from the mesothelial cells that line the pleural cavity and less commonly from the peritoneal lining of the abdomen and pelvis.
Bastian, Boris C +10 more
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Advanced Science, EarlyView.This study reports early Piezo1 activation in bone marrow monocyte‐derived macrophages (MoMs) during myocardial infarction (MI), which governs the fate and function of recruited macrophages. The recruited MoMs with increased Piezo1 expression exhibit increased ferroptosis and defective efferocytosis, delayed clearance of dead cells and resolution of ...
Lu Peng +19 more
wiley +1 more source