Perivascular Adipose Tissue and Perivascular Adipose Tissue-Derived Extracellular Vesicles: New Insights in Vascular Disease [PDF]
CellsPerivascular adipose tissue (PVAT) is a special deposit of fat tissue surrounding the vasculature. Previous studies suggest that PVAT modulates the vasculature function in physiological conditions and is implicated in the pathogenesis of vascular ...
Smara Sigdel +3 more
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Rat perivascular adipose tissue microvasculature revealed by tissue clearing [PDF]
Frontiers in PhysiologyPerivascular adipose tissue (PVAT) surrounds the majority of blood vessels and plays diverse roles in vascular and metabolic functions. The hormonal and lipid exchange functions of PVAT require access to blood vessels.
Stephanie W. Watts +3 more
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Phenotypic and functional disparities in perivascular adipose tissue [PDF]
Frontiers in PhysiologyThe adipose tissue surrounding blood vessels is known as perivascular adipose tissue (PVAT), which represents a distinct ectopic fat depot that adheres to the majority of the vasculature.
Erling Guo, Dan Liu, Ziming Zhu
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Clinical correlates of perivascular adipose tissue in coronary artery disease and obesity [PDF]
Frontiers in PhysiologyThe adipose tissue surrounding the arterial and venous vasculature and microvasculature affects vascular reactivity and pathology, particularly when perivascular adipose tissue (PVAT) accumulates in overweight and obese states.
Sunil Upadhaya +3 more
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Crosstalk between perivascular adipose tissue and adipocyte-derived peptide in the pathogenesis of diabetic cardiomyopathy [PDF]
Cardiovascular DiabetologyDiabetic cardiomyopathy (DCM) is a prevalent complication in diabetic patients, and its pathogenic mechanism involves multiple endocrine and metabolic factors, with dyslipidemia playing a pivotal role in the pathogenesis of the disease.
Yingjie Feng +5 more
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Advances and challenges of targeting epicardial adipose tissue (EAT) and perivascular adipose tissue (PVAT) [PDF]
Cardiovascular DiabetologyClinical consensus statements have been issued for various adipose tissues (ATs), particularly regarding the diagnostic value of epicardial AT (EAT) and perivascular AT (PVAT) in cardiovascular disease.
Dan Liu +11 more
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Local large arterial perivascular adipose tissue metabolic and anatomical features are associated with hypertensive clinical outcomes: a PET/CT-based study [PDF]
Annals of MedicineObjective This study investigated the relationship between anatomical and metabolic characteristics of large arterial perivascular adipose tissue (PVAT) and hypertensive clinical outcomes using positron emission tomography-computed tomography (PET/CT ...
Hong-Yu Long +5 more
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The role of perivascular adipose tissue-secreted adipocytokines in cardiovascular disease
Frontiers in Immunology, 2023 Perivascular adipose tissue and the vessel wall are connected through intricate bidirectional paracrine and vascular secretory signaling pathways. The secretion of inflammatory factors and oxidative products by the vessel wall in the diseased segment has
Meichao Cai +8 more
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Aging Affects KV7 Channels and Perivascular Adipose Tissue-Mediated Vascular Tone
Frontiers in Physiology, 2021 Aging is an independent risk factor for hypertension, cardiovascular morbidity, and mortality. However, detailed mechanisms linking aging to cardiovascular disease are unclear.
Yibin Wang +11 more
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A Differential Pattern of Batokine Expression in Perivascular Adipose Tissue Depots From Mice
Frontiers in Physiology, 2021 Depending on its anatomical placement, perivascular adipose tissue (PVAT) has been found to possess features more (e.g., aortic thoracic) or less (e.g., aortic abdominal) similar to brown/beige adipose tissue in mice, whereas PVAT surrounding the ...
Alberto Mestres-Arenas +12 more
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