Results 131 to 140 of about 31,079 (213)

Mild Short‐Term Caloric Restriction Induces Coordinated Changes That Promote Lipid Deposition While Maintaining Thermogenesis Capacity in Interscapular Brown Adipose Tissue of Male Rats

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Rats under mild caloric restriction (85% vs. ad libitum) for 2 weeks show metabolic and structural adaptations in iBAT. Caloric restriction increases glycolysis and triglyceride deposition in the tissue, leading to larger lipid droplets. It also reduces mitochondrial iBAT content, while maintaining iBAT thermogenic potential thanks to an increased ...
Giuliana Panico, Vincenzo Migliaccio, Gabriella Pinto, Anna Iliano, Gianluca Fasciolo, Martina Coletta, Paola Venditti, Maria Moreno, Angela Amoresano, Pieter de Lange, Lillà Lionetti, Assunta Lombardi   +11 more
wiley   +1 more source

Body fat distribution: the answer to the apparent paradox of obesity in cardiology?

Ожирение и метаболизм, 2017
Today, despite all the measures taken, cardiovascular diseases remain the main cause of temporary invalidization, disability and mortality. Obesity is a major risk factor of cardiovascular diseases and complications from them. However, not all fat depots
Daria A. Borodkina, Olga V. Gruzdeva, Ludmila V. Kvitkova, Olga L. Barbarash   +3 more
doaj   +1 more source

Concise review on clinical applications of conditioned medium derived from human umbilical cord-mesenchymal stem cells (UC-MSCS) [PDF]

, 2018
In recent years, mesenchymal stem cells have provoked much attentiveness in the field of regenerative medicine because of their differentiation potential and the capability to facilitate tissue repair via the emancipation of biologically active molecules.
Banerjee, Antara, Di Liddo, Rosa, Gopinath, Madhumala, Jothimani, Ganesan, Marotta, Francesco, Murugesan, Ramachandran, Pathak, Surajit, Sriramulu, Sushmitha   +7 more
core  

Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress [PDF]

, 2018
Aim. Nonalcoholic steatohepatitis (NASH) is the consequence of insulin resistance, fatty acid accumulation, oxidative stress, and lipotoxicity.We hypothesize that an increase in the inflammatory adipokine NOV decreases antioxidant Heme Oxygenase 1 (HO- 1)
Abraham, Nader G., Bamshad, David, Bellner, Lars, Favero, Gaia, Grant, Ilana, Lebovics, Edward, Meissner, Aliza, Raffaele, Marco, Rezzani, Rita, Rodella, Luigi F., Sacerdoti, David, Schragenheim, Joseph, Singh, Shailendra P., Vanella, Luca   +13 more
core   +1 more source

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Human decellularized dermal matrix seeded with adipose-derived stem cells enhances wound healing in a murine model : experimental study [PDF]

, 2019
Objective: Full-thickness cutaneous wounds treated with split-thickness skin grafts often result in unaesthetic and hypertrophic scars. Dermal substitutes are currently used together with skin grafts in a single treatment to reconstruct the dermal layer ...
Amos, Anderson, Banyard, Blanton, Blecher, Cao, Davis, de Vries, Dominici, Foltynski, Foubert, Greenhalgh, Hendrickx, Holder, Huang, Jang, Kataoka, Kilkenny, Kilroy, Kim, Koh, Lu, Michaels, Moon, Nambu, Nguyen, Nie, Nie, Pirayesh, Rasband, Rowan, Seo, Sivan, Truong, Tsuboi, Wainwright, Wang, Zannettino   +37 more
core   +2 more sources

Glucagon‐Like Peptide‐1 Targets in the Human Nodose Ganglion

Journal of Comparative Neurology, Volume 534, Issue 2, February 2026.
Our findings demonstrate that the human nodose ganglion expresses Glp1r mRNA and reveal species similarities and differences in Glp1r expression between humans and mice. ABSTRACT Given the rapidly expanding clinical use of glucagon‐like peptide‐1 receptor (GLP1R) agonists—well‐known for their antidiabetic and antiobesity effects—it is increasingly ...
Warda Merchant, Claire Mackaaij, Cindy G. J. Cleypool, Laurent Gautron   +3 more
wiley   +1 more source

Assessment of coronary artery outward remodeling in consequence of excision of epicardial adipose tissue in Ossabaw swine [PDF]

, 2017
Background Coronary artery disease (CAD) results from the buildup of cholesterol, inflammatory factors, and proliferating smooth muscle cells within a vessel wall. This plaque impedes on the vessel lumen, decreasing the space through which blood can flow,
Coderre, Kelly
core   +1 more source

Cytologic and Histologic Findings of Extrapleural Solitary Fibrous Tumor: Report of Two Cases

Diagnostic Cytopathology, Volume 54, Issue 2, Page E46-E53, February 2026.
ABSTRACT Solitary fibrous tumors (SFT) are a rare neoplasm of mesenchymal origin. SFT was previously described primarily in the pleura and meninges; however, extrapleural and extra‐meningeal SFT have been reported in almost every anatomic site and account for up to 40% of cases.
Michael Tyler, Katsiaryna Khatskevich, Chadi Hajar, Jack Yang, Hao Liu   +4 more
wiley   +1 more source