Results 141 to 150 of about 31,079 (213)

Advances in the Role of Adipose Tissue in Promoting Injury Repair and Resist Infection

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background In recent years, adipose tissue (AT) transplantation has increasingly been noticed by many people in the field of tissue repair and regeneration. Accumulating evidence demonstrates that AT exerts dual functions in promoting tissue repair and conferring anti‐infective properties, with distinct biological effects attributed to its ...
Xi Duan, Run Li, Lei Fu, Jiali Yang, Zhean Zhan   +4 more
wiley   +1 more source

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen, Binghua Li, Shengjia Wang, Yongzhong Yao, Zhao Huang, Decai Yu   +5 more
wiley   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

Stem cells from human cardiac adipose tissue depots show different gene expression and functional capacities

Stem Cell Research & Therapy, 2019
Background The composition and function of the adipose tissue covering the heart are poorly known. In this study, we have investigated the epicardial adipose tissue (EAT) covering the cardiac ventricular muscle and the EAT covering the left anterior ...
Carmen Lambert, Gemma Arderiu, Maria Teresa Bejar, Javier Crespo, Maribel Baldellou, Oriol Juan-Babot, Lina Badimon   +6 more
doaj   +1 more source

Recent Insights Into Circulating Adipokines in Obesity: Systematic Review and Meta‐Analysis

Obesity Science &Practice, Volume 12, Issue 1, February 2026.
ABSTRACT Background Adipokines are dysregulated in obesity and exacerbate proinflammatory conditions. Although several studies have investigated adipokine levels in obesity, their findings have been inconsistent, leaving the precise nature of these alterations uncertain.
Sunita Sunita, Mohammad Ghozali, Mohammad Rizki Akbar, Annisa Dewi Nugrahani, Iis Inayati Rakhmat, Siti Nur Fatimah, Yuni Susanti Pratiwi, Eko Fuji Ariyanto, Gaga Irawan Nugraha, Mas Rizky A. A. Syamsunarno, Tri Hanggono Achmad   +10 more
wiley   +1 more source

Context‐Dependent Roles of ANGPTL2‐Mediated Inflammaging in Tissue Homeostasis, Pathological Tissue Remodeling, and Longevity

Aging Cell, Volume 25, Issue 2, February 2026.
Yumoto et al. show that ANGPTL2 regulates inflammation, fibrosis, and tissue remodeling in high‐fat diet‐induced premature aging. ANGPTL2 deficiency shortens lifespan but reduces inflammation, revealing its context‐dependent and organ‐specific roles in maintaining homeostasis.
Shinsei Yumoto, Haruki Horiguchi, Keishi Miyata, Tsuyoshi Kadomatsu, Zhe Tian, Michio Sato, Kimi Araki, Masaaki Iwatsuki, Yuichi Oike   +8 more
wiley   +1 more source

Heart matters: How glucose‐ and lipid‐modulating drugs remodel epicardial adipose tissue accumulation, inflammatory patterns and browning

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 878-894, February 2026.
Abstract Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot located between the myocardium and the visceral pericardium, exerting direct paracrine and vasocrine effects on the heart and coronary vessels. Under physiological conditions, EAT supports myocardial energy metabolism and thermoregulation through fatty acid supply and
Elisabeth Heuboeck, Charnkamal Singh Bhogal, Markus Mandl   +2 more
wiley   +1 more source

WHO classification of skin tumours: key updates in the fifth edition

Histopathology, Volume 88, Issue 3, Page 555-568, February 2026.
This review article summarizes the key updates in the 5th edition of the WHO Classification of Skin Tumours. It provides an overview of the major changes and new entities specific to the skin section, covering areas such as epidermal, melanocytic, mesenchymal and other tumours. The 5th edition of the World Health Organization Classification of Tumours (
Gabrielle Goldman‐Lévy, Raymond Barnhill, Boris C. Bastian, Werner Kempf, David Elder, Pedram Gerami, Wayne Grayson, Dmitry Kazakov, Daniela Massi, Jane Messina, Arnaud de la Fouchardière, Alexander J. Lazar, Thomas Brenn, Brian Rous, Andrew Field, Anthony Gill, Jennelle C. Hodge, Joseph D Khoury, Katia Leite, Shahin Sayed, Puay Hoon Tan, Rosalie Elenitsas, Eduardo Calonje, Lyn M. Duncan, Liang Zhiyong, Holger Moch, Rajendra Singh, Harshima Wijesinghe, Ian Cree, Dilani Lokuhetty   +29 more
wiley   +1 more source

Exercise effects on perivascular adipose tissue

British journal of pharmacology, 2017
Obesity is a global epidemic, accompanied by increased risk of type 2 diabetes and cardiovascular disease. Adipose tissue hypertrophy is associated with adipose tissue inflammation, which alters the secretion of adipose tissue-derived bioactive products, known as adipokines.
Boa, B. C.S., Yudkin, J. S., van Hinsbergh, V. W.M., Bouskela, E., Eringa, E. C.   +4 more
openaire   +1 more source

Comparison of Human Mesenchymal Stem Cells Derived from Various Compartments of Human Adipose Tissue and Tunica Adventitia Layer of the Arteries Subsequent to Organ Donation

International Journal of Organ Transplantation Medicine, 2019
Background: Mesenchymal stem cells are one of the most interesting cell sources used in regenerative medicine. Objective: In the present study, we isolated and characterized the mesenchymal stem cells from various compartments of human adipose tissue ...
M Kaviani, N Azarpira, M Hossein Aghdaie, E Esfandiari, B Geramizadeh, S Nikeghbalian, M Dehghani   +6 more
doaj