Results 61 to 70 of about 31,079 (213)
Perivascular adipose tissue: more than just structural support [PDF]
Clinical Science, 2011 PVAT (perivascular adipose tissue) has recently been recognized as a novel factor in vascular biology, with implications in the pathophysiology of cardiovascular disease. Composed mainly of adipocytes, PVAT releases a wide range of biologically active molecules that modulate vascular smooth muscle cell contraction, proliferation and migration.
Theodora, Szasz, R Clinton, Webb
openaire +4 more sources
Ovalbumin sensitization and challenge increases the number of lung cells possessing a mesenchymal stromal cell phenotype [PDF]
, 2010 Background Recent studies have indicated the presence of multipotent mesenchymal stromal cells (MSCs) in human lung diseases. Excess airway smooth muscle, myofibroblasts and activated fibroblasts have each been noted in asthma, suggesting that ...
Adam M Goldsmith +8 more
core +6 more sources
AntioxidantsThe NADPH oxidase NOX4 that releases H2O2 can mediate vasoprotective mechanisms under pathophysiological conditions in conductive arteries. However, the role of NOX4 in resistance arteries and in perivascular adipose tissue is not well understood.
Patrick Diaba-Nuhoho +4 more
doaj +1 more source
Anti‐atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis [PDF]
, 2017 Background and Purpose: Inflammation plays a key role in atherosclerosis. A protective role of angiotensin-(1-7) in vascular pathologies opened a possibility for therapeutic use of small molecule non-peptide Ang-(1-7) mimetics, such as AVE0991.
Czesnikiewicz-Guzik, M. +11 more
core +2 more sources
Lean and Obese Coronary Perivascular Adipose Tissue Impairs Vasodilation via Differential Inhibition of Vascular Smooth Muscle K+ Channels [PDF]
, 2015 OBJECTIVE: The effects of coronary perivascular adipose tissue (PVAT) on vasomotor tone are influenced by an obese phenotype and are distinct from other adipose tissue depots. The purpose of this investigation was to examine the effects of lean and obese
Goodwill, Adam G. +4 more
core +1 more source
AdipocyteInflammatory changes in perivascular adipose tissue are associated with atherosclerotic lesions in the adjacent artery and can also be used as a marker in patient workup.
Hana Bartuskova +8 more
doaj +1 more source
Targeting inflammation to reduce cardiovascular disease risk [PDF]
, 2017 This joint themed section of the British Journal of Pharmacology and the British Journal of Clinical Pharmacology stems from a joint British Pharmacological Society – Italian Society of Pharmacology symposium held at the 37th National Congress of the ...
Cirino, Guiseppe, Maffia, Pasquale
core +1 more source
Microphysiological Systems of Lymphatics and Immune Organs
Advanced Healthcare Materials, EarlyView.This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
Molecular Metabolism, 2018 Objective: Perivascular adipose tissue depots around the aorta are regionally distinct and have specific functional properties. Thoracic aorta perivascular adipose tissue (tPVAT) expresses higher levels of thermogenic genes and lower levels of ...
Khanh-Van Tran +4 more
doaj +1 more source
Терапевтический архив, 2022 Aim. To determine the frequency, distribution and characteristics of ectopic obesity in patients without manifested cardiovascular disease. Materials and methods. We examined 320 patients without manifested cardiovascular disease (average age 63.813.9
Valery I. Podzolkov +6 more
doaj +1 more source