Perivascular space dysfunction in cerebral small vessel disease is related to neuroinflammation [PDF]
BrainEnlarged perivascular spaces are a feature of cerebral small vessel disease, and it has been hypothesized that they might reflect impaired glymphatic drainage.
Daniel Tozer +2 more
exaly +11 more sources
Functional analysis of the human perivascular subarachnoid space [PDF]
Nature CommunicationsThe human subarachnoid space harbors the cerebrospinal fluid, which flows within a landscape of blood vessels and trabeculae. Functional implications of subarachnoid space anatomy remain far less understood.
Per Kristian Eide, Geir Ringstad
doaj +2 more sources
Disproportionate subarachnoid space hydrocephalus—outcome and perivascular space [PDF]
Annals of Clinical and Translational Neurology, 2014 AbstractObjectiveWe sought to identify the prevalence of MRI features of disproportionately enlarged subarachnoid space hydrocephalus in possible idiopathic normal pressure hydrocephalus (DESH‐iNPH) and to describe the clinico‐radiological features and outcomes of a community‐based investigation (The Vienna Trans‐Danube Aging study).MethodsOf the 697 ...
Akiguchi, Ichiro +10 more
openaire +5 more sources
Perivascular Spaces and the Two Steps to Neuroinflammation [PDF]
Journal of Neuropathology & Experimental Neurology, 2008 Immune cells enter the central nervous system (CNS) from the circulation under normal conditions for immunosurveillance and in inflammatory neurologic diseases. This review describes the distinct anatomic features of the CNS vasculature that permit it to maintain parenchymal homeostasis and which necessitate specific mechanisms for neuroinflammation to
Owens, Trevor +2 more
openaire +5 more sources
Responses of perivascular macrophages to circulating lipopolysaccharides in the subfornical organ with special reference to endotoxin tolerance [PDF]
Journal of Neuroinflammation, 2019 Background Circulating endotoxins including lipopolysaccharides (LPS) cause brain responses such as fever and decrease of food and water intake, while pre-injection of endotoxins attenuates these responses.
Shoko Morita-Takemura +9 more
doaj +2 more sources
The Configuration of the Perivascular System Transporting Macromolecules in the CNS [PDF]
Frontiers in Neuroscience, 2019 Large blood vessels entering the CNS are surrounded by perivascular spaces that communicate with the cerebrospinal fluid and, at their termini, with the interstitial space.
Beata Durcanova +12 more
doaj +3 more sources
Perivascular network segmentations derived from high-field MRI and their implications for perivascular and parenchymal mass transport in the rat brain [PDF]
Scientific Reports, 2023 A custom segmentation workflow was applied to ex vivo high-field MR images of rat brains acquired following in vivo intraventricular contrast agent infusion to generate maps of the perivascular spaces (PVS).
Julian A. Rey +6 more
doaj +2 more sources
Giant Tumefactive Perivascular Spaces with Obstructive Hydrocephalus: A Case Report [PDF]
, 2023 The perivascular space is a normal anatomical structure that forms around perforating arteries and is filled with cerebrospinal fluid. In rare cases, the perivascular space is enlarged and form multiocular cysts measuring 1.5 cm or larger, which are ...
Akutsu, Hiroyoshi +4 more
core +3 more sources
Linear regression analyses for factors associated with the enlarged perivascular space scores. [PDF]
, 2021 Linear regression analyses for factors associated with the enlarged perivascular space scores.
Hyun-Woo Nam (3056094) +3 more
core +1 more source
Glymphatic dysfunction and cognitive impairment in tuberculous meningitis: insights from diffusion tensor imaging along the perivascular space (DTI-ALPS). [PDF]
Front NeurosciWang Y +5 more
europepmc +3 more sources