Results 41 to 50 of about 43,516 (333)

Brain perivascular space imaging across the human lifespan

NeuroImage, 2023
Enlarged perivascular spaces (PVS) are considered a biomarker for vascular pathology and are observed in normal aging and neurological conditions; however, research on the role of PVS in health and disease are hindered by the lack of knowledge regarding ...
Kirsten M. Lynch, Farshid Sepehrband, Arthur W. Toga, Jeiran Choupan   +3 more
doaj   +1 more source

The Influence of Demographics and Vascular Risk Factors on Glymphatic Function Measured by Diffusion Along Perivascular Space

Frontiers in Aging Neuroscience, 2021
Assessing glymphatic function using in-vivo imaging method is of great value for understanding its contribution to major brain diseases. In the present study, we aim to validate the association between a variety of risk factors and a potential index of ...
Yao Zhang, Ruiting Zhang, Yongquan Ye, Shuyue Wang, Yeerfan Jiaerken, Hui Hong, Kaicheng Li, Qingze Zeng, Xiao Luo, Xiaopei Xu, Xinfeng Yu, Xiao Wu, Wenke Yu, Minming Zhang, Peiyu Huang   +14 more
doaj   +1 more source

Role of perivascular and meningeal macrophages in outcome following experimental subarachnoid hemorrhage [PDF]

, 2021
The distribution and clearance of erythrocytes after subarachnoid hemorrhage (SAH) is poorly understood. We aimed to characterize the distribution of erythrocytes after SAH and the cells involved in their clearance. To visualize erythrocyte distribution,
Wan, Hoyee, Hynynen, Kullervo, Ai, Jinglu, Brathwaite, Shakira, Macdonald, R. Loch   +4 more
core   +1 more source

Lipopolysaccharide induced inflammation in the perivascular space in lungs-0 [PDF]

, 2011
E monocytes/macrophages (D). MCP-1 expression is demonstrated on the apical epithelium and on the endothelium and most of the leukocytes as well (E control, F MCP-1).Copyright information:Taken from "Lipopolysaccharide induced inflammation in the ...
Reinhard Pabst (95533), Kyathanahalli S Janardhan (95532), Baljit Singh (40367), Thomas Tschernig (95531)   +3 more
core   +1 more source

Perivascular space and neurological disorders [PDF]

Neuroscience Bulletin, 2009
Perivascular space (PVS) is a crevice between two slices of cerebral pia maters, filled with tissue fluid, which be formed by pia mater emboling in the surrounding of cerebral perforating branch (excluding micrangium). Normal PVS (diameter < 2 mm) can be found in almost all healthy adults; however enlarged PVS (diameter > 2 mm) has correlation with ...
openaire   +2 more sources

Lipopolysaccharide induced inflammation in the perivascular space in lungs [PDF]

, 2008
Background Lipopolysaccharide (LPS) contained in tobacco smoke and a variety of environmental and occupational dusts is a toxic agent causing lung inflammation characterized by migration of neutrophils and monocytes into alveoli.
Janardhan Kyathanahalli S, Singh Baljit, Pabst Reinhard, Tschernig Thomas   +3 more
core   +1 more source

Does Long-Duration Exposure to Microgravity Lead to Dysregulation of the Brain and Ocular Glymphatic Systems?

Eye and Brain, 2022
Peter Wostyn,1 Thomas H Mader,2 Charles Robert Gibson,3,4 Maiken Nedergaard5,6 1Department of Psychiatry, PC Sint-Amandus, Beernem, Belgium; 2Colonel, US Army (Retired), Moab, UT, USA; 3Coastal Eye Associates, Webster, TX, USA; 4KBR, NASA Space Medicine ...
Wostyn P, Mader TH, Gibson CR, Nedergaard M   +3 more
doaj  

Mechanisms of Glioma Formation: Iterative Perivascular Glioma Growth and Invasion Leads to Tumor Progression, VEGF-Independent Vascularization, and Resistance to Antiangiogenic Therapy

Neoplasia: An International Journal for Oncology Research, 2014
As glioma cells infiltrate the brain they become associated with various microanatomic brain structures such as blood vessels, white matter tracts, and brain parenchyma.
Gregory J. Baker, Viveka Nand Yadav, Sebastien Motsch, Carl Koschmann, Anda-Alexandra Calinescu, Yohei Mineharu, Sandra Ines Camelo-Piragua, Daniel Orringer, Serguei Bannykh, Wesley S. Nichols, Ana C. deCarvalho, Tom Mikkelsen, Maria G. Castro, Pedro R. Lowenstein   +13 more
doaj   +1 more source

Cognitive Impairment in Chronic Kidney Disease Is Associated with Glymphatic System Dysfunction

Kidney Diseases, 2023
Introduction: This study was designed to explore the associations between impaired cognition in chronic kidney disease (CKD) patients and the dysfunction of the glymphatic system. Method: Data were obtained from 77 CKD patients and 50 age-matched healthy
Shuqin Xu, Jiuqi Wang, Kedi Sun, Lin Meng, Chi Qin, Renyi Feng, Yiming Tian, Yanping Zhai, Dongxiao Liang, Rui Zhang, Haiyan Tian, Han Liu, Yongkang Chen, Yu Fu, Pei Chen, Qingyong Zhu, Junfang Teng, Xuejing Wang   +17 more
doaj   +1 more source

Spatial coupling of enlarged perivascular spaces and white matter lesions across the Alzheimer's disease continuum

Frontiers in Neuroscience
IntroductionEmerging evidence suggests that impaired waste-clearance systems contribute to Alzheimer's disease pathogenesis, yet the etiology of clearance dysfunction markers, such as enlarged perivascular spaces, remains unclear.
Serena Tang, Serena Tang, Pamela Thropp, Isabella Hausle, Kyan Younes, Duygu Tosun, Duygu Tosun   +6 more
doaj   +1 more source