Results 61 to 70 of about 43,516 (333)

Burden of dilated perivascular spaces in patients with moyamoya disease and moyamoya syndrome is related to middle cerebral artery stenosis

open access: yesFrontiers in Neurology, 2023
Background and objectiveThe correlation between intracranial large artery disease and cerebral small vessel disease (CSVD) has become a noteworthy issue.
Guangsong Han   +7 more
doaj   +1 more source

Glymphatic System in the Central Nervous System, a Novel Therapeutic Direction Against Brain Edema After Stroke

open access: yesFrontiers in Aging Neuroscience, 2021
Stroke is the destruction of brain function and structure, and is caused by either cerebrovascular obstruction or rupture. It is a disease associated with high mortality and disability worldwide.
Xiangyue Zhou   +5 more
doaj   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu   +11 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan   +14 more
wiley   +1 more source

Perivascular fluid clearance links choroid plexus changes to cognitive performance in cerebral small vessel disease

open access: yesBrain Informatics
Choroid plexus (CP) dysfunction may impair cerebrospinal fluid (CSF) turnover and perivascular glymphatic clearance, but whether CP microstructural injury correlates to cerebral small vessel disease (CSVD)-related brain alteration and cognitive ...
Dan Luo   +8 more
doaj   +1 more source

New Insights in Addressing Cerebral Small Vessel Disease: Association With the Deep Medullary Veins

open access: yesFrontiers in Aging Neuroscience, 2020
ObjectiveTo assess the suitability of deep medullary vein visibility in susceptibility weighted imaging—magnetic resonance imaging studies as a method for the diagnosis and evaluation of cerebral small vessel disease progression.MethodsA total of 92 ...
Zhihua Xu   +11 more
doaj   +1 more source

Sleep, Perivascular Spaces, and Cognition in Alzheimer's Disease and Parkinson's Disease [PDF]

open access: yes, 2022
Cognitive dysfunction, particularly involving memory and executive function, is a core component of neurodegenerative conditions, such as Alzheimer’s disease and Parkinson’s disease.
Tatham, Erica Lee
core  

Additional file 1 of Increased glymphatic system activity in migraine chronification by diffusion tensor image analysis along the perivascular space [PDF]

open access: yes, 2023
Additional file 1: Figure S1. Correlations between headache intensity and DTI-ALPS index both in the left hemisphere (a) and right hemisphere (b) before Bonferroni correction (p < 0.0025, statistical significance).
Xueyan Zhang (277449)   +14 more
core   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang   +17 more
wiley   +1 more source

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