Results 71 to 80 of about 43,516 (333)

Expanding cerebellar lacunes due to dilatation of the perivascular space associated with Binswanger's subcortical arteriosclerotic encephalopathy. [PDF]

, 1987
An 80-year-old hypertensive woman developed right hemiplegia and died 24 hours after admission. Neuropathologic examination revealed multiple cerebral infarcts of various ages and diffuse subcortical arteriosclerotic encephalopathy.
F Gray, N Benhaïem-Sigaux, A M Roucayrol, R Gherardi, J Poirier   +4 more
core   +1 more source

A Novel Perfused Full‐Thickness Human Skin Microphysiological System for Modeling Injury, Regeneration, Tumor Pathophysiology, and Therapeutics Development

Advanced Healthcare Materials, EarlyView.
What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu, Hamid Malekzadeh, Alexa Rivera Del Rio Hernandez, Naresh Mahajan, Ethan Banks, Dayyan Ur Rahman, José A. Arellano, Katherine S. Yang, Alexey Altman, G.V. Naveen Kumar, Matthew L. Steinhauser, Jeffrey A. Gusenoff, J. Peter Rubin, Asim Ejaz   +13 more
wiley   +1 more source

Perivascular Spaces, Glymphatic System and MR

Frontiers in Neurology, 2022
The importance of the perivascular space (PVS) as one of the imaging markers of cerebral small vessel disease (CSVD) has been widely appreciated by the neuroradiologists. The PVS surrounds the small blood vessels in the brain and has a signal consistent with the cerebrospinal fluid (CSF) on MR.
Linya Yu, Xiaofei Hu, Haitao Li, Yilei Zhao   +3 more
openaire   +3 more sources

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Rapid and Widespread Distribution of Intranasal Small Extracellular Vesicles Derived from Mesenchymal Stem Cells throughout the Brain Potentially via the Perivascular Pathway

Pharmaceutics, 2023
Intranasal administration is a promising strategy to enhance the delivery of the sEVsomes-based drug delivery system to the central nervous system (CNS).
Weiwei Shen, Tongyao You, Wenqing Xu, Yanan Xie, Yingzhe Wang, Mei Cui   +5 more
doaj   +1 more source

The Triglyceride Glucose Index Is a Risk Factor for Enlarged Perivascular Space [PDF]

, 2022
Yazhen Cai, Binxiong Chen, Xiaoyi Zeng, Meirong Xie, Xiaolan Wei, Jiangping Cai   +5 more
openalex   +1 more source

Elastic characteristics of the lung perivascular interstitial space [PDF]

, 1983
An analysis of the elastic behavior of the lung perivascular interstitial space during interstitial fluid accumulation is presented. Fluid accumulation must deform the lung parenchyma and vascular walls that form the interstitial space boundaries.
J. C. Smith, W. Mitzner
core   +1 more source

Immunohistochemical Characterization of Proliferative Lesions in the Thymus of Aging CD-1 Mice from Two Studies on the RITA Database, with Special Reference to the Perivascular Space [PDF]

, 2022
308328Thymic lymphoid hyperplasia is a common age-related finding, which occurs particularly in female CD-1 mice. The main differential diagnoses are malignant lymphoma and thymoma.
Kellner, Rupert, Funk, J., Leonard, C., Rittinghausen, Susanne, Ruehl-Fehlert, C.   +4 more
core   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

A Multidimensional “Source-Dynamics-Function-Structure” Magnetic Resonance Imaging Framework for Characterizing the Pathophysiological Imaging Profile of Moderate-to-Advanced Parkinson’s Disease Eligible for Deep Brain Stimulation

Brain Science Advances
Objective: To characterize glymphatic- and cerebrospinal fluid (CSF)-related imaging alterations in moderate-to-advanced, deep brain stimulation (DBS)-eligible Parkinson’s disease (PD) using a multidimensional magnetic resonance imaging (MRI) framework ...
Liying Sun, Suhua Miao, Rongsong Zhou, Zhihua Zhang, Tiange Lu, Tiemin Li, Mingyuan Yan, Yu Ma, Yuqi Zhang   +8 more
doaj   +1 more source