Results 91 to 100 of about 43,516 (333)
Hemoglobin's α‐Helix‐to‐β‐Sheet Transition Enables Targeted mRNA Delivery to the Lung
Advanced Science, EarlyView.Acidic heating converts hemoglobin into β‐sheet‐rich fibrils with positively charged surfaces. These hemoglobin fibrils electrostatically complex IL‐11 scFv mRNA, selectively bind circulating platelets, and hitchhike to the lung, where they are enriched in fibroblasts.
Xihua Liu +11 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo +6 more
wiley +1 more source
Enlarged Perivascular Spaces in a Diverse Community‐based Sample. The Multi‐Ethnic Study of Atherosclerosis [PDF]
, 2023 Sokratis Charisis +21 more
openalex +1 more source
Quality Thresholds for Angiogenesis Under Acoustic Manipulation in Engineered Vascular Tissues
Advanced Science, EarlyView.Defined biological and physical quality thresholds achieved through acoustic manipulation regulate cellular alignment and spatial organization, promoting self‐assembling vasculature, extracellular matrix deposition, and angiogenic responses, thereby establishing critical acoustic patterning requirements for engineered vascular tissue development in ...
Oscar O'Dwyer Lancaster‐Jones +5 more
wiley +1 more source
Zhongguo cuzhong zazhi目的 通过文献计量学的方法分析2013—2023年血管周围间隙的研究现状、热点及前沿领域。 方法 在Web of Science核心合集数据库中检索2013年1月1日—2023年6月19日血管周围间隙相关英文论著。使用CiteSpace V6.3.R1软件分析文献的发文国家、研究机构、作者的合作网络，参考文献、第一作者、期刊的共被引网络，关键词的共现网络，关键词及参考文献共被引的突现情况；使用VOSviewer 1.6.15软件对关键词进行聚类分析。 结果 共纳入1549篇文献。2013 ...
杨营营1，王伊龙1，2，3，4，5，6 (YANG Yingying1, WANG Yilong1,2,3,4,5,6 )
doaj +1 more source
Author Correction: Dispersion as a waste-clearance mechanism in flow through penetrating perivascular spaces in the brain [PDF]
, 2021 Daniel E. Troyetsky +3 more
openalex +1 more source
Leptin Receptor Expression in Mouse Intracranial Perivascular Cells [PDF]
, 2018 Past studies have suggested that non-neuronal brain cells express the leptin receptor. However, the identity and distribution of these leptin receptor-expressing non-neuronal brain cells remain debated.
Hua Wu +3 more
core +1 more source
Advanced Science, EarlyView.The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui +9 more
wiley +1 more source
Table_1_The Configuration of the Perivascular System Transporting Macromolecules in the CNS.DOC [PDF]
, 2019 Large blood vessels entering the CNS are surrounded by perivascular spaces that communicate with the cerebrospinal fluid and, at their termini, with the interstitial space.
Pilar Giffenig (6407990) +8 more
core +1 more source
Matrix Stiffness Induces Endothelial Network Senescence
Advanced Science, EarlyView.Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song +6 more
wiley +1 more source