Results 261 to 270 of about 5,273,568 (326)

Impairments in mitochondrial dynamics and morphology in skeletal muscle of breast cancer patients after a single paclitaxel administration

Experimental Physiology, EarlyView.
Abstract Standard chemotherapy regimens for patients with breast cancer are based on epirubicin–cyclophosphamide (EC) and paclitaxel (TAX) administrations. While it has been shown that first EC administration impairs mitochondrial homeostasis, the isolated effects of TAX have not been studied without previous chemotherapy exposure.
Joris Mallard, Elyse Hucteau, Laura Somme, Hervé Bischoff, Valérie Demais, Pauline Silvestrin, Anne‐Laure Charles, Roland Schott, Xavier Pivot, Thomas J. Hureau, Allan F. Pagano   +10 more
wiley   +1 more source

Detection of perivascular spaces at the gray-white matter interface using heavily T₂-weighted MRI at 7T. [PDF]

Neuroimage
Saib G, Demir ZH, Taylor PA, Talagala SL, Koretsky AP.   +4 more
europepmc   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

The unique characteristics and risk factors of enlarged perivascular spaces in pediatric moyamoya disease. [PDF]

Quant Imaging Med Surg
Hou X, Xue F, Chen N, Guo J, Zhang P.
europepmc   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

Preeclampsia‐derived small extracellular vesicles disrupt blood–brain barrier integrity and activate glial cells in vitro

The Journal of Physiology, EarlyView.
Abstract figure legend This study assessed the impact of plasma‐derived small extracellular vesicles (sEVs) from healthy pregnant women and those diagnosed with late‐onset preeclampsia (PE) on the blood–brain barrier (BBB) integrity and glial cell response. PE patients had higher sEV concentrations than healthy controls.
Julián Henao‐Restrepo, José M. Murrieta‐Coxca, Christian Schmeer, Lingyu Wei, Frank Steiniger, Tanja Groten, Udo R. Markert, Diana M. Morales‐Prieto   +7 more
wiley   +1 more source

The association between enlarged perivascular spaces and muscle sympathetic nerve activity in normotensive and hypertensive humans. [PDF]

Clin Auton Res
Rim D, Pham W, Fatouleh R, Hennessy A, Schlaich M, Henderson LA, Macefield VG.   +6 more
europepmc   +1 more source

Chronic Migraine Is Associated With Region-Specific High-Grade Enlarged Perivascular Spaces: Retrospective Matched Case-Control Study. [PDF]

J Clin Neurol
Cho JW, Lee GH, Kim J.
europepmc   +1 more source

Do enlarged white matter perivascular spaces reflect brain clearance dysfunction? Insights from intrathecal contrast-enhanced MRI. [PDF]

Neuroradiology
Cengija V, Eide PK, Ringstad G.
europepmc   +1 more source