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Enlarged Perivascular Spaces and Age-Related Clinical Diseases [PDF]

Clinical Interventions in Aging, 2023
Yuyuan Yang,1 Meng Wang,1 Moxin Luan,1 Xiaoqian Song,1 Yajuan Wang,2 Lulu Xu,3 Meixiang Zhong,4 Xueping Zheng1 1Department of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China; 2Department of Geriatric
Xueping Zheng
exaly   +6 more sources

Editorial: Enlarged perivascular spaces: etiology and significance [PDF]

Frontiers in Neuroscience, 2023
Michele Cavallari, Florian Dubost, Charles R. G. Guttmann, Christopher W. Lee-Messer   +3 more
doaj   +4 more sources

Deep learning based detection of enlarged perivascular spaces on brain MRI [PDF]

NeuroImage: Reports, 2023
Deep learning has been demonstrated effective in many neuroimaging applications. However, in many scenarios, the number of imaging sequences capturing information related to small vessel disease lesions is insufficient to support data-driven techniques ...
Tanweer Rashid, Hangfan Liu, Jeffrey B. Ware, Karl Li, Jose Rafael Romero, Elyas Fadaee, Ilya M. Nasrallah, Saima Hilal, R. Nick Bryan, Timothy M. Hughes, Christos Davatzikos, Lenore Launer, Sudha Seshadri, Susan R. Heckbert, Mohamad Habes   +14 more
doaj   +5 more sources

Cognitive impairment due to widespread enlarged perivascular spaces

Radiology Case Reports, 2021
Perivascular spaces, also known as Virchow-Robin spaces, are usually considered as a normal, asymptomatic finding. However, this finding can occasionally demonstrate an atypical appearance and can be symptomatic. We report herein a rare case of cognitive
Yoshitaka Yamaguchi, MDPhD, Manabu Wada, MDPhD, Luna Kimihira, MDPhD, Hikaru Nagasawa, MDPhD   +3 more
doaj   +3 more sources

Correlation between the neutrophil‐to‐lymphocyte ratio and enlarged perivascular spaces in type 2 diabetes mellitus [PDF]

Journal of Diabetes Investigation
Aims To determine the relationship between the neutrophil‐to‐lymphocyte ratio and enlarged perivascular spaces in patients with type 2 diabetes mellitus. Materials and Methods Cranial magnetic resonance imaging data from 200 patients with type 2 diabetes
Wei Zhang, Zhen Wang, Yaping Sun, Shaofeng Xu, Lei Zhu, Xiaolei Li   +5 more
doaj   +2 more sources

Spatial coupling of enlarged perivascular spaces and white matter lesions across the Alzheimer's disease continuum [PDF]

Frontiers in Neuroscience
IntroductionEmerging evidence suggests that impaired waste-clearance systems contribute to Alzheimer's disease pathogenesis, yet the etiology of clearance dysfunction markers, such as enlarged perivascular spaces, remains unclear.
Serena Tang, Serena Tang, Pamela Thropp, Isabella Hausle, Kyan Younes, Duygu Tosun, Duygu Tosun   +6 more
doaj   +2 more sources

Enlarged perivascular spaces, neuroinflammation and neurological dysfunction in NMOSD patients

Frontiers in Immunology, 2022
Background and objectivesCerebrospinal fluid (CSF) and interstitial fluid exchange along a brain-wide network of perivascular spaces (PVS) termed the ‘glymphatic system’.
Xiao-Ying Yao, Mei-Chun Gao, Shu-Wei Bai, Li Xie, Ya-Ying Song, Jie Ding, Yi-Fan Wu, Chun-Ran Xue, Yong Hao, Ying Zhang, Yang-Tai Guan   +10 more
doaj   +3 more sources

Enlarged Perivascular Spaces Among Hispanic and Latino Adults in SOL‐INCA‐MRI [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background To examine preliminary associations between enlarged perivascular spaces (ePVS) and cerebrovascular small‐vessel disease, cortical atrophy, and cognitive impairment among a select cohort of Hispanic and Latino adults.
Tuyet T. Nguyen, Baljeet Singh, Daniel Schwartz, Lisa Silbert, Carmen R. Isasi, Paola F. Villegas, Fernando D. Testai, Martha Daviglus, Linda C. Gallo, Gregory A. Talavera, Ariana Stickel, Christian Agudelo, Alberto R. Ramos, Tatjana Rundek, Natasha Anita, Daniela Sotres‐Alvarez, Wassim Tarraf, Hector Gonzalez, Charles DeCarli   +18 more
doaj   +2 more sources

Enlarged perivascular spaces are linked to freezing of gait in Parkinson's disease

Frontiers in Neurology, 2022
ObjectiveFreezing of gait (FOG) is one of common and disabling gait impairments of Parkinson's disease (PD). White matter hyperintensity (WMH) and lacunes, as common manifestations of cerebral small vessel diseases (CSVD), have been reported to be ...
Fangju Lin, Baoling Yang, Ying Chen, Wei Zhao, Binghan Li, Weihua Jia   +5 more
doaj   +3 more sources

“Mind the Gap”—enlarged perivascular spaces as a potential magnetic resonance imaging biomarker of impaired glymphatic clearance in brain disorders [PDF]

Frontiers in Cellular Neuroscience
The abundant capillary network penetrating the brain parenchyma is surrounded by potential tubular, fluid-filled regions referred to as perivascular spaces (PVSs).
Claudia F. Kirsch, Claudia F. Kirsch, Claudia F. Kirsch, Mackenzie Herb, Guarav Verma, Priti Balchandani   +5 more
doaj   +2 more sources