A Closer Look at the Perivascular Unit in the Development of Enlarged Perivascular Spaces in Obesity, Metabolic Syndrome, and Type 2 Diabetes Mellitus [PDF]
BiomedicinesThe recently described perivascular unit (PVU) resides immediately adjacent to the true capillary neurovascular unit (NVU) in the postcapillary venule and contains the normal-benign perivascular spaces (PVS) and pathological enlarged perivascular spaces (
Melvin Hayden, Hayden Melvin R
exaly +4 more sources
Deep Cascade of Convolutional Neural Networks for Quantification of Enlarged Perivascular Spaces in the Basal Ganglia in Magnetic Resonance Imaging [PDF]
DiagnosticsIn this paper, we present a cascaded deep convolution neural network (CNN) for assessing enlarged perivascular space (ePVS) within the basal ganglia region using T2-weighted MRI.
Seunghye Chae +3 more
doaj +4 more sources
Giant tumefactive perivascular spaces [PDF]
Radiology Case Reports, 2023 Perivascular spaces are parts of the glymphatic pathway in the brain, which are microscopic but visible on magnetic resonance imaging when enlarged. Here, we described a case of a 16-year-old boy who presented with chronic headaches.
Xiaodi Hao, PhD +4 more
doaj +2 more sources
Enlarged Perivascular Spaces and Cerebral Small Vessel Disease [PDF]
International Journal of Stroke, 2013 Background and aims Enlarged perivascular spaces (also known as Virchow-Robin spaces) on T2-weighted brain magnetic resonance imaging are common, but their etiology, and specificity to small vessel as opposed to general cerebrovascular disease or ageing, is unclear.
Potter, Gillian M. +6 more
openaire +8 more sources
Association of Apolipoprotein E ɛ4 Allele with Enlarged Perivascular Spaces [PDF]
Annals of Neurology, 2022 ObjectiveEnlarged perivascular spaces have emerged as markers of cerebral small vessel disease and are linked to perivascular drainage dysfunction. The apolipoprotein E‐ɛ4 (APOE‐ɛ4) allele is the strongest genetic risk factor for cerebral amyloid angiopathy and Alzheimer's neuropathology, but the underlying mechanisms remain unclear.
Adlin Pinheiro +7 more
openaire +5 more sources
Enlarged perivascular spaces in the basal ganglia are associated with arteries not veins. [PDF]
J Cereb Blood Flow MetabEnlarged perivascular spaces (EPVS) are common in cerebral small vessel disease (CSVD) and have been identified as a marker of dysfunctional brain clearance. However, it remains unknown if the enlargement occurs predominantly around arteries or veins.
Oltmer J +10 more
europepmc +6 more sources
Enlarged Perivascular Spaces and Dementia: A Systematic Review [PDF]
Journal of Alzheimer's Disease, 2019 Perivascular compartments surrounding the penetrating arteries in the brain are part of a physiologic system, which facilitates fluids exchange and clearance of solutes from the brain. The perivascular compartments become visible on MRI when enlarged and are commonly referred to as perivascular spaces (ePVS). Previous studies on the association between
Smeijer, David +2 more
openaire +5 more sources
Association of enlarged perivascular spaces and anticoagulant-related intracranial hemorrhage [PDF]
Neurology, 2020 To investigate whether enlarged perivascular spaces (PVS) within the basal ganglia or deep cerebral white matter are risk factors for intracranial hemorrhage in patients taking oral anticoagulants (OACs), independent of established clinical and radiologic risk factors, we conducted a post hoc analysis of Clinical Relevance of Microbleeds in Stroke ...
Jonathan G. Best +104 more
core +11 more sources
Widespread enlarged perivascular spaces associated with dementia and focal brain dysfunction: case report [PDF]
BMC Neurology, 2017 Background Enlarged perivascular spaces (PVS) are common magnetic resonance imaging (MRI) findings, whereas widespread enlarged PVS are extremely rare.
Daisuke Taniguchi +4 more
doaj +2 more sources
Direct Rating Estimation of Enlarged Perivascular Spaces (EPVS) in Brain MRI Using Deep Neural Network [PDF]
Applied Sciences, 2021 In this article, we propose a deep-learning-based estimation model for rating enlarged perivascular spaces (EPVS) in the brain’s basal ganglia region using T2-weighted magnetic resonance imaging (MRI) images. The proposed method estimates the EPVS rating
Ehwa Yang +6 more
doaj +5 more sources