Results 31 to 40 of about 5,273,568 (326)

Periarteriolar spaces modulate cerebrospinal fluid transport into brain and demonstrate altered morphology in aging and Alzheimer’s disease

Nature Communications, 2022
The precise boundaries and flow compartments of perivascular spaces in the brain are incompletely understood. Here the authors show that pia is perforated and permissive to CSF flow, forming three types of perivascular spaces that remodel with age, with ...
Humberto Mestre, Natasha Verma, Thom D. Greene, LiJing A. Lin, Antonio Ladron-de-Guevara, Amanda M. Sweeney, Guojun Liu, V. Kaye Thomas, Chad A. Galloway, Karen L. de Mesy Bentley, Maiken Nedergaard, Rupal I. Mehta   +11 more
doaj   +1 more source

Enlarged Perivascular Spaces in Relation to Cumulative Blood Pressure Exposure and Cognitive Impairment

HYPERTENSION, 2023
BACKGROUND: Hypertension and enlarged perivascular spaces (EPVS) are thought to be associated with cognitive impairment. However, the correlations among hypertension, EPVS, and cognitive impairment have not been studied yet.
Huijing Shi, L. Cui, Y. Hui, Shouling Wu, Xiaoshuai Li, R. Shu, Haicheng Song, Jie-rui Wang, P. Yu, Shuohua Chen, Jing Li, Ling Yang, Zhenchang Wang, Q. Yang, Yuxia Gao   +14 more
semanticscholar   +1 more source

Diffusion along perivascular spaces as marker for impairment of glymphatic system in Parkinson’s disease

npj Parkinson's Disease, 2022
The brain glymphatic system is involved in the clearance of misfolding α-synuclein, the impaired glymphatic system may contribute to the progression of Parkinson’s disease (PD). We aimed to analyze the diffusion tensor image along the perivascular space (
Ting Shen, Yumei Yue, Fang Ba, Tinging He, Xiaocui Tang, Xingyue Hu, J. Pu, Cong Huang, W. Lv, Baorong Zhang, Hsin-Yi Lai   +10 more
semanticscholar   +1 more source

Assessment of Risk Factors and Clinical Importance of Enlarged Perivascular Spaces by Whole-Brain Investigation in the Multi-Ethnic Study of Atherosclerosis

JAMA Network Open, 2023
Key Points Question What is the clinical importance of enlarged perivascular spaces detected on brain magnetic resonance imaging? Findings This cross-sectional study was conducted in a multiethnic sample of 1026 individuals living in the community ...
S. Charisis, T. Rashid, Hangfan Liu, J. Ware, P. Jensen, Thomas R Austin, Karl Li, Elyas Fadaee, S. Hilal, Christopher P L H Chen, T. Hughes, J. Romero, Jon B. Toledo, W. Longstreth, T. Hohman, I. Nasrallah, R. Bryan, L. Launer, C. Davatzikos, S. Seshadri, S. Heckbert, M. Habes   +21 more
semanticscholar   +1 more source

Deep Learning Based Detection of Enlarged Perivascular Spaces on Brain MRI [PDF]

Neuroimage: Reports, 2022
Deep learning has been demonstrated effective in many neuroimaging applications. However, in many scenarios, the number of imaging sequences capturing information related to small vessel disease lesions is insufficient to support data-driven techniques ...
T. Rashid, Hangfan Liu, J. Ware, Karl Li, J. Romero, Elyas Fadaee, I. Nasrallah, S. Hilal, R. Bryan, T. Hughes, C. Davatzikos, L. Launer, S. Seshadri, S. Heckbert, M. Habes   +14 more
semanticscholar   +1 more source

Perivascular Spaces: Normal and Giant [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2007
The purpose of this paper is to discuss both normal perivascular spaces (PVSs) and pathological giant perivascular spaces (GPVSs). The anatomy and physiology of normal PVSs, including important immunological and lymphatic roles, are described. Special attention is given to the Magnetic Resonance Imaging (MRI) findings of both normal and GPVSs ...
Randy, Fanous, Mehran, Midia
openaire   +2 more sources

Unusually prominent perivascular spaces [PDF]

Neurology, 2001
A 50-year-old right-handed woman was referred for evaluation of abnormal MRI studies ( figure) that were obtained because of a 2-month history of left ear pain, which had resolved in the …
G R, Eichhorn, Z, Ammache, W, Bell, W T, Yuh   +3 more
openaire   +2 more sources

The effect of prolonged spaceflight on cerebrospinal fluid and perivascular spaces of astronauts and cosmonauts

Proceedings of the National Academy of Sciences of the United States of America, 2022
Long-duration spaceflight induces changes to the brain and cerebrospinal fluid compartments and visual acuity problems known as spaceflight-associated neuro-ocular syndrome (SANS).
G. Barisano, F. Sepehrband, H. Collins, S. Jillings, B. Jeurissen, James A Taylor, Catho Schoenmaekers, Chloé De Laet, I. Rukavishnikov, Inna Nosikova, L. Litvinova, A. Rumshiskaya, J. Annen, Jan Sijbers, S. Laureys, A. van Ombergen, V. Petrovichev, V. Sinitsyn, E. Pechenkova, A. Grishin, P. zu Eulenburg, M. Law, S. Sunaert, P. Parizel, E. Tomilovskaya, D. Roberts, F. Wuyts   +26 more
semanticscholar   +1 more source

Sleep cycle-dependent vascular dynamics in male mice and the predicted effects on perivascular cerebrospinal fluid flow and solute transport

Nature Communications, 2023
Why fluid and solute transport in perivascular spaces is enhanced upon sleep remains elusive. Here, the authors show that each sleep cycle state displays unique perivascular dynamics, which enhances predicted fluid movement and solute transport.
Laura Bojarskaite, Alexandra Vallet, Daniel M. Bjørnstad, Kristin M. Gullestad Binder, Céline Cunen, Kjell Heuser, Miroslav Kuchta, Kent-Andre Mardal, Rune Enger   +8 more
doaj   +1 more source

Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology

Neuroradiology, 2021
Perivascular spaces (PVS) of the brain, often called Virchow-Robin spaces, comprise fluid, cells and connective tissue, and are externally limited by astrocytic endfeet.
Kaylene Gouveia-Freitas, A. Bastos-Leite
semanticscholar   +1 more source