Results 111 to 120 of about 3,550,881 (351)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
On order statistics from nonidentical discrete random variables
Open Physics, 2016 In this study, pf and df of single order statistic of nonidentical discrete random variables are obtained. These functions are also expressed in integral form.
Yüzbaşı Bahadır +2 more
doaj +1 more source
Journal of Indian Society of Pedodontics and Preventive Dentistry, 2017 Multiple supernumerary teeth are rare developmental anomalies which are often associated with syndromes. Only few examples of nonsyndromic supernumerary teeth have been reported with fourth, fifth, sixth, and seventh molar rarest of all.
Pallav Singhal +3 more
doaj +1 more source
The Volcanic Asymmetry or the Question of Permanent Sovereignty over Natural Disasters [PDF]
, 2014 Alejandra Mancilla
openalex +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Clinical outcome of CAD/CAM overlays of MIH affected young permanent molars
, 2023 Alaa M. Eldehna +3 more
openalex +1 more source
Migration of repetitive DNAs during evolution of the permanent translocation heterozygosity in the oyster plant (Tradescantia section Rhoeo) [PDF]
, 2022 Hieronim Golczyk +9 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Distribution and use of grasslands in the Czech Republic and biodiversity of invertebrates [PDF]
, 2008 In the Czech Republic the major focus of organic farming lies in permanent grasslands management. Animal production is mostly focused on non-milk pasture beef-raising on almost the whole farm area. By contrast conventional farms do not grass sufficiently,
Bohac, Jaroslav +4 more
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Molecular Oncology, EarlyView.The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat +18 more
wiley +1 more source