Results 61 to 70 of about 47,506 (262)

Deprem Yükleri Altında Kalıcı Şev Deplasmanlarının Tahmini

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2014
Dinamik yükleme altındaki şevlerin stabilitesi genel olarak yarı-statik analiz yöntemi kullanılarak incelenir. Bu yöntem, belirli bir güvenlik katsayısını dikkate almakla birlikte, oluşan kalıcı deplasmanlar hakkında bir bilgi vermemektedir.
Deniz Ülgen, H. Kürşat Engin
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Energy Method for Evaluating Earthquake Induced Permanent Displacement of Soil Slopes

工程科学与技术, 2010
:Since the permanent displacement induced by earthquake can be regarded as an effective criterion for stability estimation and anti-seismic design of slopes, a new method for evaluating the displacement and improve its estimating accuracy was proposed ...
Xu Guang-xing
doaj  

Seismic dynamic response analysis for tunnels considering coseismic displacement

Yantu gongcheng xuebao
Fault dislocation is a form of dynamic impact load that induces permanent deformation of the stratum in the vicinity of the fault. Based on the finite-fault source and crustal velocity model, coseismic displacement is computed according to the layered ...
FENG Jun1, 2 , ZHAO Boming1, 2 , WANG Zijun1, 2
doaj   +1 more source

Quasi-Equilibrium Stress Zone with Residual Displacement Causing Permanent Slippage in Shrink-Fitted Sleeve Rolls

Metals, 2018
Rolling back-up rolls require high fracture toughness, particularly in the shaft portion, and high-hardness in the sleeve portion. The rolls are classified into two types; one is an integrated type and the other is a shrink-fitted type consisting of a ...
Nao-Aki Noda, Hiromasa Sakai, Yoshikazu Sano, Yasushi Takase, Yutaro Shimoda   +4 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Bayesian network based probabilistic approach for uncertainty analysis of earthquake induced landslides

Soils and Foundations
In this study, a unique approach is used to calculate the likelihood of the safety factor and permanent displacement of natural slopes under earthquake shaking.
Tanmoy Das, Deepankar Choudhury
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Regularity of Cross-Fault Ground Motion Input Characteristics on the Response of Transmission Tower-Line Systems

Buildings
Transmission tower-line systems spanning active faults are simultaneously subjected to the “dual characteristic seismic actions” of permanent ground displacement (PGD) and spatially varying near-fault ground motions, rendering their failure mechanisms ...
Yu Wang, Xiaojun Li, Mianshui Rong
doaj   +1 more source