Results 51 to 60 of about 47,506 (262)

Displacement field of the Italian area from permanent GPS stations

Annals of Geophysics, 1998
A network of nine permanent GPS stations, six of them located in Italy (Cagliari, Matera, Medicina, Noto, Padova and Torino), the other three in Central Europe (Graz, Zimmervald and Wettzell) was been analyzed four times from October 1996 till 1998 ...
A. Zanutta, F. Riguzzi
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Static-Dynamic response and permanent displacement forecast for high cutting slope pre-reinforced by pile

工程科学与技术, 2010
: The slopes in western mountains are used to be developed into the infrastructure construction for the scarcity of land resources. However, it usually lead to collapse and causes great damage for improper cut slope. Here based on the upper bound theorem
He siming
doaj  

Seismic Response of a Large-Span Steel Truss Arch Bridge under Nonuniform Near-Fault Ground Motions

Buildings
The ground motion in the near-fault region of an earthquake is characterized by exceptional energy levels, powerful velocity impulses, substantial spatial variability, and notable permanent displacement.
Zhen Liu, Xingliang Ma, Junlin Lv
doaj   +1 more source

Severe Impaction of the Primary Mandibular Second Molar Accompanied by Displacement of the Permanent Second Premolar

Case Reports in Dentistry, 2015
Tooth impaction is defined as any tooth that fails to erupt into a normal functional position and remains unerupted beyond the time at which it should normally erupt. Reports of impaction and eruption failure in primary teeth are relatively rare compared
Junko Matsuyama, Shoko Kinoshita-Kawano, Sachiko Hayashi-Sakai, Tomoe Mitomi, Tomiko Sano-Asahito   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Review of fault models for reproducing and predicting strong ground motions and permanent displacements—findings in the 2016 Kumamoto earthquake

Japan Architectural Review
For accurate evaluation of the impact of earthquakes to structures in the vicinity of the earthquake faults, it has been required to develop appropriate calculation methods for short‐ and long‐period ground motions and permanent displacements.
Kazuo Dan
doaj   +1 more source

Permanent displacement of slopes under multi-point earthquake ground motions considering site effects

Yantu gongcheng xuebao
The nonlinear dynamic response of slope soils caused by seismic motion may lead to inconsistent time histories of seismic acceleration at different positions of a slope.
SONG Jian1, 2 , PAN Yuhang2, LU Zhuxi2, JI Jian1, 2, ZHANG Fei1, 2, GAO Yufeng1, 2
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source