Results 41 to 50 of about 49,772 (296)

Dynamic characteristics of a bitable linear actuator with moving permanent magnet [PDF]

Serbian Journal of Electrical Engineering, 2004
The dynamic characteristics of an ax symmetrical linear actuator with axially magnetized moving permanent magnet are obtained using combined field and circuit approach.
Yatchev Ivan, Hinov Krastio, Gueorgiev Vultchan   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Using the Newmark Sliding Block Method to Construct the Empirical Model of Permanent Displacement for Earthquake-Induced Landslides in China

Applied Sciences
Earthquakes and the secondary hazards they trigger, such as landslides, collapses, and debris flows, profoundly reshape the land surface and cause significant casualties, property damage and ecological disruption.
Feng Liu, Faqiao Qian, Jie Liu, Chihui Guo, Hao Liu, Yahong Deng, Maosheng Zhang   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Non-Return and Non-Arrival in Aboriginal Australia. Comment on Isayev (2021). Ancient Wandering and Permanent Temporariness. Humanities 10: 91

Humanities, 2022
This dialogue constitutes an engagement with Elena Isayev’s article, “Ancient Wandering and Permanent Temporariness”. It focusses on concepts Elena has marshalled for the analysis of ancient and contemporary experiences of displacement (“non-return ...
Paul Magee, Paul Collis
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The Influence of Subgrade Subsidence on Train Track Dynamic Interaction

, 2012
Railways 2012 The First International Conference on Railway Technology: Research, Development and Maintenance Las Palmas de Gran Canaria, Spain 18-20 April 2012This paper reports results from a numerical model to calculate subgrade settlement in ...
E.J. OBrien, O'Brien, Eugene J., Gavin, Kenneth, A. Taheri, Taheri, A., K. Gavin   +5 more
core   +1 more source

Reinforcement effects of optimal strategy of anti-slide piles on irregular slopes with bedding rock slopes under near-fault ground motions

Yantu gongcheng xuebao
In practical engineering, the surfaces of bedding rock slopes are mostly irregular, and their geometrical concave and convex characteristics and joint characteristics have a significant effect on the slope stability, which leads to the problem of the ...
YANG Yansong 1 , XIAO Yu 1, LI Dejian 1 , CHENG Xiao 2, YU Qiangshan 1, YU Pengcheng 1
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Buried pipelines with bends: analytical verification against permanent ground displacements [PDF]

Canadian Geotechnical Journal, 2016
Available analytical methodologies for the stress analysis of buried pipelines against large permanent ground displacements (PGDs) apply only to straight pipeline segments. Hence, a new methodology is proposed herein for the analytical computation of pipeline strains in bends of arbitrary angle and radius of curvature, located outside the PGD high ...
Karamitros, Dimitrios K., Zoupantis, Christos, Bouckovalas, George   +2 more
openaire   +2 more sources