Results 31 to 40 of about 45,406 (263)
Advances in Mechanical Engineering, 2021 Permanent magnet linear motors can cause thrust fluctuation due to cogging and end effects, which will affect the operation stability of the linear motor.
Feng Zhou +3 more
doaj +1 more source
Buried pipelines with bends: analytical verification against permanent ground displacements [PDF]
Canadian Geotechnical Journal, 2016 Available analytical methodologies for the stress analysis of buried pipelines against large permanent ground displacements (PGDs) apply only to straight pipeline segments. Hence, a new methodology is proposed herein for the analytical computation of pipeline strains in bends of arbitrary angle and radius of curvature, located outside the PGD high ...
Karamitros, Dimitrios K. +2 more
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Yantu gongcheng xuebaoIn practical engineering, the surfaces of bedding rock slopes are mostly irregular, and their geometrical concave and convex characteristics and joint characteristics have a significant effect on the slope stability, which leads to the problem of the ...
YANG Yansong 1 , XIAO Yu 1, LI Dejian 1 , CHENG Xiao 2, YU Qiangshan 1, YU Pengcheng 1
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Dynamic characteristics of a bitable linear actuator with moving permanent magnet [PDF]
Serbian Journal of Electrical Engineering, 2004 The dynamic characteristics of an ax symmetrical linear actuator with axially magnetized moving permanent magnet are obtained using combined field and circuit approach.
Yatchev Ivan +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Humanities, 2022 This dialogue constitutes an engagement with Elena Isayev’s article, “Ancient Wandering and Permanent Temporariness”. It focusses on concepts Elena has marshalled for the analysis of ancient and contemporary experiences of displacement (“non-return ...
Paul Magee, Paul Collis
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source