Results 31 to 40 of about 47,506 (262)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A new method of phase-shifting and displacement of unit motor to suppress the thrust fluctuation of linear motor

Advances in Mechanical Engineering, 2021
Permanent magnet linear motors can cause thrust fluctuation due to cogging and end effects, which will affect the operation stability of the linear motor.
Feng Zhou, Han Zhao, Xiaoke Liu, Fujia Wang   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Reinforcement effects of optimal strategy of anti-slide piles on irregular slopes with bedding rock slopes under near-fault ground motions

Yantu gongcheng xuebao
In practical engineering, the surfaces of bedding rock slopes are mostly irregular, and their geometrical concave and convex characteristics and joint characteristics have a significant effect on the slope stability, which leads to the problem of the ...
YANG Yansong 1 , XIAO Yu 1, LI Dejian 1 , CHENG Xiao 2, YU Qiangshan 1, YU Pengcheng 1
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Dynamic characteristics of a bitable linear actuator with moving permanent magnet [PDF]

Serbian Journal of Electrical Engineering, 2004
The dynamic characteristics of an ax symmetrical linear actuator with axially magnetized moving permanent magnet are obtained using combined field and circuit approach.
Yatchev Ivan, Hinov Krastio, Gueorgiev Vultchan   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Displacement and Dilaceration of Permanent Teeth as a sequel of trauma to Primary Teeth diagnosed by CBCT: A Rare Case Report

Orthodontic Journal of Nepal, 2016
Dentoalveolar trauma to the primary teeth can result in displacement, dilaceration, discoloration, delayed eruption and impaction of permanent teeth. Displacement and dilaceration of permanent teeth is the most common sequel of such injuries.
Pooja Pokharel, Shruti B Nimbeni, Basavaraj S Nimbeni, Sourav K Rout   +3 more
doaj   +1 more source