Results 151 to 160 of about 1,849,496 (250)

A Bioinspired Underwater Soft Robot for Active Intravesical Liquid Delivery and Mixing

open access: yesAdvanced Intelligent Systems, EarlyView.
A bioinspired underwater soft robot is reported that integrates an elastic strain energy‐driven soft robotic pump with a programmable flexible magnetic valve, enabling remotely controlled, programmable, and sustained liquid release and mixing. This functionality is enabled by the synergistic integration of elastic strain energy‐driven pumping and ...
Jacob Katona   +7 more
wiley   +1 more source

T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy

open access: yesAnnals of Neurology, EarlyView.
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes   +6 more
wiley   +1 more source

Visual Responsivity in Autism: Measuring Visual Responses in Autistic and Non‐Autistic Adults Using Psychophysics, fMRI, and EEG

open access: yesAutism Research, EarlyView.
ABSTRACT Autistic individuals frequently report heightened sensitivity to visual stimuli, often described as discomfort in environments with bright or flickering lights. These experiences are hypothesized to reflect underlying differences in sensory gain or neural hyperexcitability; however, findings across studies have yielded mixed results, likely ...
Daniela L. Seczon   +6 more
wiley   +1 more source

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci   +10 more
wiley   +1 more source

Nacre‐inspired layered composite with excellent mechanical support and osteogenic potential for cervical interbody cage

open access: yesBMEMat, EarlyView.
The cervical interbody cage needs to take both biomechanical and biological requirements into account. Here, a new‐style degradable, multicomponent, and bioinspired nacre‐like cervical interbody cage composite, which exhibits promising mechanical‐support‐related behavior and osteogenesis‐related potential, is designed and prepared.
Xiu‐Wu Guo   +8 more
wiley   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

open access: yesBMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen   +9 more
wiley   +1 more source

Methanol With Increased Water Content in Internal Combustion Engines

open access: yesChemie Ingenieur Technik, EarlyView.
This study investigates the potential to improve overall Well‐to‐Wheel efficiency by using low‐purity methanol from synthesis of hydrogen and furnace gas as CO2‐source. Combustion efficiency is comparable to pure methanol, while distillation energy could be saved.
Maximilian Dobberkau   +3 more
wiley   +1 more source

Large droplet release

open access: yesDroplet, EarlyView.
Curved hydrophobic mesh surfaces enable stable release of large droplets exceeding the capillary length. By tuning surface curvature, porosity, and acceleration, oscillatory breakup is suppressed, producing near‐spherical droplets ideal for high‐precision fluid applications and multiphase flow control.
Aqeel Almanashi   +6 more
wiley   +1 more source

Occipital irregular delta activity in focal epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Nonspecific occipital irregular delta activity (OID) is a common finding in focal epilepsy (FE). However, the significance of OID and its relationship to the underlying etiology of FE remain largely unstudied. This study aimed to investigate the relationship between OID and the etiology of FE, as well as the relationship between OID ...
Mónika Bessenyei   +3 more
wiley   +1 more source

Refining diagnostic boundaries and electroclinical profiles of Lennox–Gastaut syndrome through unsupervised clustering

open access: yesEpilepsia, EarlyView.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a developmental and epileptic encephalopathy defined by polymorphic seizures, intellectual disability (ID), and characteristic electroencephalographic (EEG) patterns. The applicability and biological validity of current electroclinical criteria remain debated.
Emanuele Cerulli Irelli   +12 more
wiley   +1 more source

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