Results 31 to 40 of about 3,380,119 (245)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Bulletin of "Carol I" National Defense UniversityThe Permanent Structured Cooperation is a successful initiative through which the European Union develops military capabilities necessary for strengthening the European dimension of security and defence.
Marius PRICOPI
doaj +1 more source
Permanent Sovereign COoperation (PESCO) to underpin the EU Global Strategy. Egmont Security Policy Brief No. 80 December 2016 [PDF]
, 2016 The EU now has a full-fledged Global Strategy for Foreign and Security Policy – and defence. Just in time. The EUGS includes a clear political level of ambition as well as a call to define the corresponding military level of ambition and the required ...
Coelmont, Joel.
core
Global Cooperation and Economies of Recognition: The Case of NGOs [PDF]
, 2014 Transnational non-governmental organizations (NGOs) are commonly regarded either as agents of empire or as manifestations of the progressive enlightenment of humankind.
Heins, Volker M.
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Permanent structured cooperation in defence: building effective European armed forces. Bruges Political Research Papers No. 15, September 2010 [PDF]
, 2010 Sven Biscop and Jo Coelmont outline a concrete proposal to implement Permanent Structured Cooperation, the new mechanism introduced by the Lisbon Treaty in the area of the Common Security and Defence Policy.
Biscop, Sven, Coelmont, Jo.
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The Constraints of Power Structures on EU Integration and Regulation of Military Procurement
European Papers, 2021 (Series Information) European Papers - A Journal on Law and Integration, 2021 6(1), 831-868 | Article | (Table of Contents) I. Introduction. - II. Legal structures of military integration and cooperation in the EU. - II.1.
Nathan Meershoek
doaj +1 more source