Results 91 to 100 of about 2,545,611 (287)

PKCε and cardioprotection : an exploration of putative mechanisms [PDF]

, 2006
Includes bibliographical references.Recent studies have investigated the underlying regulatory mechanisms that may explain the cardioprotective role of PKCε.
McCarthy, Joy
core   +1 more source

One-dimensional fluid diffusion induced by constant-rate flow injection: Theoretical analysis and application to the determination of fluid permeability and specific storage of a cored rock sample [PDF]

, 2004
We describe the conceptual design and first application of a new method for simultaneously measuring the fluid permeability and specific storage of a rock sample.
Song, I., Odling, N. W., Smyth, N. F., Ngwenya, B. T., Elphick, S. C., Main, I. G.; id_orcid   +5 more
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

A small-molecule DS44170716 inhibits Ca2+-induced mitochondrial permeability transition

Scientific Reports, 2017
Mitochondria are involved in a variety of physiological and pathological processes. Ca2+ uptake is one of the important functions of the organelle for maintenance of cellular Ca2+ homeostasis.
Naohiro Kon, Atsushi Satoh, Naoki Miyoshi   +2 more
doaj   +1 more source

The effects of micronutrient-fortified complementary/replacement food on intestinal permeability and systemic markers of inflammation among maternally HIV-exposed and unexposed Zambian infants. [PDF]

, 2011
The present randomised trial investigated the effects of feeding Zambian infants from 6 to 18 months old either a richly or basal micronutrient-fortified complementary/replacement food on gut integrity and systemic inflammation.
Chisenga, Molly, Mullen, Anne, Filteau, Suzanne, Anne Mullen, Molly Chisenga, Suzanne Filteau, Laura Gosset, Gosset, L, Chisenga, M, Gosset, Laura, Larke, Natasha, Filteau, S, Manno, Daniela, Kasonka, Lackson, Mullen, A, Larke, N, Kasonka, L, Manno, D, Lackson Kasonka, Natasha Larke, Daniela Manno   +20 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

A Pore–Fracture Permeability Model for Rocks, Considering Temperature-Induced Damage and Creep Deformation

Applied Sciences
Deep rock engineering is affected by coupled thermal, mechanical, and hydraulic processes, and the accurate prediction of permeability evolution is important for underground energy development and engineering safety.
Xueying Liu, Wendi Tu, Jin Yu, Di Wu, Chen Jin, Zhigang Yan   +5 more
doaj   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Kinetic Analysis of the Mitochondrial Permeability Transition

Journal of Biological Chemistry, 1996
The permeability transition process in rat liver mitochondria was studied by following the swelling consequent to external solute equilibration through the membrane pore. The kinetics of the transition was analyzed according to a model based on the assumptions that the transition rate follows a first-order process and that the solute diffusion rate ...
openaire   +3 more sources

An Experimental Investigation into Using Electro-Chemical Properties to Measure Permeability in Low Permeability Formations [PDF]

, 2016
Permeability is one of the most important property in the study of rock formations. Different permeability measurement techniques have been used in the industry, some of which are based on modelling while others on experiments.
Kazi, Tabish
core