Results 181 to 190 of about 279,150 (304)

Synaptophysin autoantibodies mediate synaptic dysfunction in cerebellar ataxia. [PDF]

Cell Rep Med
Ho S, Wong HK, Shqau D, Winklmeier S, Grobe-Einsler M, Rostasy K, Kümpfel T, Thaler FS, Brimberg L, Schneider MA, Muley T, Vural A, Seifert-Held T, Endmayr V, Höftberger R, Faber J, Klopstock T, Frahm S, Gerdes LA, Meinl E, Mader S.   +20 more
europepmc   +1 more source

Nuclear Pore Mechanotransduction in Oncology: A Structural Axis of Vulnerability for Targeted Intervention

Advanced Materials, EarlyView.
Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Yun Qian, Wei‐En Yuan, Victor Shahin   +5 more
wiley   +1 more source

Nrf2 modulates cytosolic and mitochondrial calcium signal. [PDF]

Redox Biol
Preziuso A, Baev AY, Rustamova FR, Naidu SD, Millichap L, Angelova PR, Lariccia V, Dinkova-Kostova AT, Abramov AY.   +8 more
europepmc   +1 more source

Multilayered Digital Microfluidic Chip for Cell‐Based Assays

Advanced Materials Interfaces, EarlyView.
A multilayered digital microfluidic (mDMF) chip architecture is introduced to improve throughput and robustness in cell‐based assays. By multilayering electrode components and dielectric layers on glass, this design significantly reduces actuation voltage, maintains reliability, and enables expansion of the operational area with minimum current leakage.
Mert Ozden, Oksana K. Savchak, Burcu Gumuscu   +2 more
wiley   +1 more source

Voltage-gated calcium channels as key regulators of neuronal differentiation in the immortalized dorsal root ganglion neuronal cell line F11. [PDF]

Sci Rep
López D, Brea J, Barro M, Loza MI, Martínez AL.   +4 more
europepmc   +1 more source

Flexible Wide Bandgap Electrode System for In situ Cell Sensing and Irreversible Electroporation

Advanced Materials Interfaces, EarlyView.
The paper reports the design and wafer‐level microfabrication of a long‐lived, flexible 3C‐SiC electrode capable of sensitive and in situ cell sensing, as well as electroporation ablation. The work demonstrates a biocompatible and durable electrode platform that can perform reliable electrical interfacing with biological tissues over extended periods ...
Minh Anh Huynh, Sharda Yadav, Tuan‐Khoa Nguyen, Nam‐Trung Nguyen   +3 more
wiley   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

A kinetic assay of mitochondrial ADP-ATP exchange rate in permeabilized cells. [PDF]

Anal Biochem, 2010
Kawamata H, Starkov AA, Manfredi G, Chinopoulos C.   +3 more
europepmc   +1 more source

Spheroid‐On‐A‐Drop: A Modular Droplet Microfluidics Platform

Advanced Materials Technologies, EarlyView.
The proposed Spheroid‐on‐a‐Drop platform represents a reproducible and tunable platform for the fabrication of biocompatible GelMA‐based microgels, able to support controlled 3D tumor spheroid culture. Its precise control over droplet dynamics and cell distribution paves the way for advanced applications in tissue modeling, drug screening, and ...
A. Fergola, V. Vighetto, G. Mesiano, A. Cosola, S. L. Marasso, M. Cocuzza, C. F. Pirri, L. Napione, F. Frascella   +8 more
wiley   +1 more source

A Case Report of Reversible Mitochondrial Bioenergetic Dysfunction in PBMCs in Anti-GAD65-Associated Cerebellar Ataxia. [PDF]

Cerebellum
Huňarová N, Verešpejová AI, Grófik M, Sivák Š, Kurča E, Kolísek M, Skáčik P.   +6 more
europepmc   +1 more source