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Effect of permeation enhancers and organic acids on the skin permeation of indapamide

International Journal of Pharmaceutics, 2008
The aim of present study was to investigate the transdermal properties of indapamide and to explore the efficacy of various permeation enhancers and organic acids with regard to the percutaneous absorption of indapamide. Permeation experiments were performed in vitro, using rat abdominal skin as a barrier. In the permeation studies, 2-chamber diffusion
Changshun, Ren   +5 more
openaire   +2 more sources

Intestinal Permeation Enhancers

Journal of Pharmaceutical Sciences, 2000
This review addresses the field of improving oral bioavailability through the use of excipients that increase intestinal membrane permeability. The critical issues to consider in evaluating these approaches are 1) the extent of bioavailability enhancement achieved, 2) the influence of formulation and physiological variables, 3) toxicity associated with
openaire   +2 more sources

Permeate

2015
The permeate is the whole mass permeated of the membrane containing the different species which permeated the membrane itself.
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[Influence of permeation enhancers on transdermal permeation of anemonin].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008
To investigate the effect of different permeation enhancer on transdermal permeation of anemonin through human skin.The permeation experiments were performed using human skin on modified Franz diffusion cells in vitro. The concentrations of anemonin in receptor compartment at specified time points were determined by HPLC.
Yu-Ming, Ning   +2 more
openaire   +1 more source

The Impact of Permeation Enhancers on Transcellular Permeation of Small Molecule Drugs

The Journal of Physical Chemistry B
Passive permeation through an epithelial membrane may be enhanced by using a class of amphiphilic molecules known as permeation enhancers (PEs). PEs have been studied in clinical trials and used in coformulations with peptides and small molecule drugs, and yet, an understanding of the permeant-PE interactions leaves much to be desired.
Mabel Bernaldez   +4 more
openaire   +2 more sources

Graphene synthesized by chemical vapor deposition as a hydrogen isotope permeation barrier

Carbon, 2021
Katherine T Young   +2 more
exaly  

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