Results 121 to 130 of about 66,692 (339)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

STRUCTURAL-SEMANTIC TYPES OF THE COMBINATION OF THE VERB LASSEN WITH AN INFINITIVE

Вестник Кемеровского государственного университета, 2017
The  article  examines  the  combination  of  the  German  verb  lassen with an infinitive as an entire infinitival structure, where each component influences the creation of grammatical meanings of the whole structure. On the basis of this point of view
O. A. Smetanina
doaj   +1 more source

An investigation of premarital sexual permissiveness of Wisconsin State University-La Crosse students

, 1970
The purpose of this study was to determine the premarital sexual permissiveness of a population sampling of upper class students at University of Wisconsin - La Crosse. The subjects were 109 unmarried, on campus University students.
Reedich, John C.
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Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Inheritance Law and Investment in Family Firms [PDF]

Entrepreneurs may be constrained by the law to bequeath a minimal stake to non-controlling heirs. The size of this stake can reduce investment in family firms, by reducing the future income they can pledge to external financiers.
Marco Pagano, Andrew Ellul, Fausto PAnunzi   +2 more
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Il-4rα-dependent Lung Macrophage Response To Helminth Increases Permissiveness To Gammaherpesvirus Infection

, 2021
Helminth infection conditions lung macrophages in the long term, but little is known about how helminths affect the lung macrophage responses to respiratory viral coinfection.
Wathieu, Caroline, Rolot, Marion, Hornsell, William, Dewals, Benjamin G, Petrellis, Georgios, Chariot, Alain, Chetty, Alisha, Preure, Amira, Dougall, Annetter   +8 more
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Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Hubungan tipe cinta dengan premarital sexual permissiveness pada dewasa muda

, 2017
"Permisivitas terhadap perilaku seks pranikah semakin meningkat. Salah satu faktor yang memengaruhi permisivitas terhadap perilaku seks pranikah adalah cinta (Reiss, 1964). Penelitian ini bertujuan untuk menguji hubungan tipe cinta (eros, ludus, storge,
Mulyaputri, Inten
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