Results 101 to 110 of about 66,692 (339)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Journal of Tropical Medicine, 2012 Infection with dengue virus presents a broad clinical spectrum, which can range from asymptomatic cases to severe cases that are characterised by haemorrhagic syndrome and/or shock. The reason for such variability remains unknown. This work evaluated the
Jeanette Prada-Arismendy +2 more
doaj +1 more source
Sexting in Serbia: Prevalence and relationship with attitudes towards sexuality and sexual risk behaviour [PDF]
Sociološki PregledThe main aim of this study was to examine the frequency of sexting among students in Serbia, as well as its association with attitudes about sexuality and risky sexual behaviour.
Stanojević Dragana Z. +2 more
doaj +1 more source
Quantifying Permissiveness of Access Control Policies
International Conference on Software Engineering, 2022 William Eiers +5 more
semanticscholar +1 more source
Prevention Science, 2014 To enhance prevention efforts to reduce college drinking, parents have been identified as an important source of influence that can be modified with brief interventions.
Lindsey Varvil-Weld +4 more
semanticscholar +1 more source
Examining the scalability of intimacy permissiveness scale in Taiwan
, 2012 [[abstract]]This paper examines the scalability of intimacy permissiveness measures in Taiwan by using island-wide survey data. Among models for scaling analysis, the Guttman scaling model and two latent class models – the latent-distance model and ...
Liao, Pei-shan;Su-hao Tu
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Communication & Society (Formerly Comunicación y Sociedad), 2019 This paper analyses the pre-professional journalistic culture of Ecuador, Cuba and Venezuela based on the degree of permissiveness held by Journalism students in regard to controversial ethical practices and their views of the media and the journalistic ...
Martín Oller-Alonso +2 more
doaj +1 more source
Permission versus permissive marketing [PDF]
Interactive Marketing, 2001 About four years ago Seth Godin coined the phrase ‘permission marketing’. It was an attempt to provide a handy catchphrase to describe a new marketing ideology, and resulted in a best-selling book and a new career for Seth as a public speaker. Unfortunately most of the folks who read the book and heard the speeches just got it wrong.
openaire +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source