Results 81 to 90 of about 66,692 (339)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Ecology and Evolution, 2022 Maintenance of variation in aposematic traits within and among populations is paradoxical because aposematic species are normally under positive frequency‐dependent predation (PFD), which is expected to erode variation. Aposematic traits can evolve in an
Aditya Ponkshe, John A. Endler
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Molecular Therapy: Oncolytics, 2014 Multiple studies have indicated that in addition to direct oncolysis, virotherapy promotes an antitumor cytotoxic T cell response important for efficacy.
Jennifer L Leddon +16 more
doaj +1 more source
Covenant Complexity in Credit Agreements: EBITDA Permissiveness and Credit Spread Outcomes
, 2022 EBITDA is a widely used metric of corporate profitability, used in the vast majority of US syndicated loan agreements; however, minimal research has occurred regarding variation within the contract-to-contract definition of EBITDA. Using machine learning
Bhutoria, Raj
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Revista Española de Sanidad Penitenciaria, 2011 Objetivos: El objetivo principal del estudio fue comparar la aceptación, adherencia, tolerancia y seguridad de varias pautas cortas para el tratamiento de la infección tuberculosa latente (TIT), frente a una estándar de 9 meses, en tratamiento ...
G. López, M. Wood, F.J. Ayesta
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Measuring permissiveness in parity games: mean-payoff parity games revisited
, 2011 We study nondeterministic strategies in parity games with the aim of computing a most permissive winning strategy. Following earlier work, we measure permissiveness in terms of the average number/weight of transitions blocked by a strategy.
Markey, Nicolas +7 more
core +1 more source