Results 71 to 80 of about 13,661 (279)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Theory and Practice of Permutation Entropy [PDF]

Proceedings of 4th International Electronic Conference on Entropy and Its Applications, 2017
Permutation entropy is a relatively new promising concept for measuring complexity of time series and of the systems behind with applications in various fields. The idea of permutation entropy it is to quantify the amount of up and down in a time series on the base of considering the distribution of ordinal patterns in it.
Karsten Keller, Inga Stolz
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Fault Recognition Method of Transmission Gear based on Morphological Wavelet and Permutation Entropy

Jixie chuandong, 2019
Based on the in-depth study on morphological wavelet with permutation entropy，a new method for gear of transmission fault recognition is proposed. Firstly，the definition of morphological wavelet is introduced，and the morphological Haar wavelet is used to
Ding Wei, Zhang Zhigang, Yao Lianhong, Huang Jie   +3 more
doaj  

Epileptic Seizure Prediction Based on Permutation Entropy [PDF]

Frontiers in Computational Neuroscience, 2018
Epilepsy is a chronic non-communicable disorder of the brain that affects individuals of all ages. It is caused by a sudden abnormal discharge of brain neurons leading to temporary dysfunction. In this regard, if seizures could be predicted a reasonable period of time before their occurrence, epilepsy patients could take precautions against them and ...
Yanli Yang, Mengni Zhou, Yan Niu, Conggai Li, Rui Cao, Bin Wang 0020, Pengfei Yan, Yao Ma, Jie Xiang 0002   +8 more
openaire   +3 more sources

Measuring center of pressure signals to quantify human balance using multivariate multiscale entropy by designing a force platform [PDF]

, 2013
Copyright © 2013 by the authors. To assess the improvement of human body balance, a low cost and portable measuring device of center of pressure (COP), known as center of pressure and complexity monitoring system (CPCMS), has been developed for data ...
Huang, C-W, Jiang, BC, Shieh, J-S, Sue, PD, Maysam F. Abbod, Bernard Jiang, Jiann-Shing Shieh, Huang, CW, Maysam Abbod, Pei-Der Sue, Shieh, JS, Abbod, MF, Bernard C. Jiang, Cheng-Wei Huang, Sue, P-D   +14 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Numerical and experimental study of the effects of noise on the permutation entropy

New Journal of Physics, 2015
We analyze the effects of noise on the permutation entropy of dynamical systems. We take as numerical examples the logistic map and the Rössler system.
C Quintero-Quiroz, S Pigolotti, M C Torrent, C Masoller   +3 more
doaj   +1 more source