Results 61 to 70 of about 13,661 (279)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Multiscale permutation entropy for two-dimensional patterns

open access: yesPattern Recognition Letters, 2021
Abstract Complexity measures are important to understand and analyze systems with one dimensional data. However, extension of these methods to images (two dimensional data) are much less usual. Bidimensional multiscale sample entropy ( M S E 2 D ) has recently been proposed as a new complexity measure for texture evaluation. However,
Morel, Cristina, Humeau-Heurtier, Anne
openaire   +2 more sources

Depth of anaesthesia assessment using interval second-order difference plot and permutation entropy techniques

open access: yes, 2017
This study presents a new method to apply the interval second-order difference plot (ISODP) and interval permutation entropy (IPE) techniques to assess the depth of anaesthesia (DoA).
Wen, Peng, Li, Tianning
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Classification of Hepatitis Viruses from Sequencing Chromatograms Using Multiscale Permutation Entropy and Support Vector Machines

open access: yes, 2019
Classifying nucleic acid trace files is an important issue in molecular biology researches. For the purpose of obtaining better classification performance, the question of which features are used and what classifier is implemented to best represent the ...
Aşkın, Öyküm Esra   +3 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Vital Sign Signal Extraction Method Based on Permutation Entropy and EEMD Algorithm for Ultra-Wideband Radar

open access: yesIEEE Access, 2019
The noncontact measurement of vital sign signals is useful for medical care, rescuing disaster survivors from ruins and public safety. In this paper, a novel vital sign signal extraction method based on permutation entropy (PE) and ensemble empirical ...
Degui Yang, Zhengliang Zhu, Buge Liang
doaj   +1 more source

Identification of Denatured Biological Tissues Based on Time-Frequency Entropy and Refined Composite Multi-Scale Weighted Permutation Entropy during HIFU Treatment

open access: yes, 2019
Identification of denatured biological tissue is crucial to high intensity focused ultrasound (HIFU) treatment. It is not easy for intercepting ultrasonic scattered echo signals from HIFU treatment region.
Bei Liu, Shengyou Qian, Weipeng Hu
core   +1 more source

Characterizing Normal and Pathological Gait through Permutation Entropy [PDF]

open access: yes, 2018
Cerebral palsy is a physical impairment stemming from a brain lesion at perinatal time, most of the time resulting in gait abnormalities: the first cause of severe disability in childhood.
David Gómez-Andrés   +16 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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