Results 31 to 40 of about 736,089 (295)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Zinc improves salt tolerance by increasing reactive oxygen species scavenging and reducing Na+ accumulation in wheat seedlings

Biologia Plantarum, 2014
Salt decreases the uptake of Zn and other minerals and causes nutritional disorders in plants. Zn is an essential micronutrient for all organisms and it is reasonable to hypothesize that Zn status is essential for maintaining salt tolerance in plants. In
L. H. Xu, W. Y. Wang, J. J. Guo, J. Qin, D. Q. Shi, Y. L. Li, J. Xu   +6 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Comparison of antioxidant responses to cadmium and lead in Bruguiera gymnorrhiza seedlings

Biologia Plantarum, 2012
Seedlings of mangrove plant Bruguiera gymnorrhiza cultured in sand with Hoagland's nutrient solution were treated with 1 to 30 mM Cd(NO3)2 or Pb(NO3)2 for 2 months.
Y. M. Tao, Y. Z. Chen, T. Tan, X. C. Liu, D. L. Yang, S. C. Liang   +5 more
doaj   +1 more source

Combined Application of Trichoderma harzianum and Paclobutrazol to Control Root Rot Disease Caused by Rhizoctonia solani of Tomato Seedlings

Agronomy, 2022
Many root diseases can cause serious damage to tomato (Solanum lycopersicum L.) production during the seedling growth period, particularly Rhizoctonia solani, Pythium spp., and Alternaria spp.
Tarek A. Shalaby, Naglaa Taha, Hossam S. El-Beltagi, Hassan El-Ramady   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The effect of exogenously applied nitric oxide on photosynthesis and antioxidant activity in heat stressed chrysanthemum

Biologia Plantarum, 2011
The effect of exogenously applied nitric oxide on the heat tolerance of Chrysanthemum morifolium was investigated by applying the NO donor sodium nitroprusside (SNP).
W. Yang, Y. Sun, S. Chen, J. Jiang, F. Chen, W. Fang, Z. Liu   +6 more
doaj   +1 more source

Antioxidants Application Enhances Regeneration and Conversion of Date Palm (Phoenix dactylifera L.) Somatic Embryos

Plants, 2022
Many embryogenic systems have been designed to generate somatic embryos (SEs) with the morphology, biochemistry, and vigor uniformity of zygotic embryos (ZEs).
Amal F. M. Zein El Din, Rasmia S. S. Darwesh, Mohamed F. M. Ibrahim, Gehan M. Y. Salama, Ibrahim M. Shams El-Din, Walid B. Abdelaal, Ghada A. Ali, Maha S. Elsayed, Ismail A. Ismail, Eldessoky S. Dessoky, Yasmin M. R. Abdellatif   +10 more
doaj   +1 more source

Nanostructures for peroxidases [PDF]

Frontiers in Molecular Biosciences, 2015
Peroxidases are enzymes catalyzing redox reactions that cleave peroxides. Their active redox centers have heme, cysteine thiols, selenium, manganese, and other chemical moieties. Peroxidases and their mimetic systems have several technological and biomedical applications such as environment protection, energy production, bioremediation, sensors and ...
Carmona-Ribeiro, Ana M., Prieto, Tatiana, Nantes, Iseli L.   +2 more
openaire   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source