Results 211 to 220 of about 273,396 (304)

WT1‐Targeted Oral Bifidobacterium longum Vaccine Enhances Checkpoint Blockade Efficacy in Pancreatic Cancer

Advanced Science, EarlyView.
Oral WT1‐targeted Bifidobacterium longum vaccine promotes WT1‐associated cellular immunity and enhances anti‐PD‐1/anti‐CTLA‐4 efficacy in pancreatic cancer. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains largely unresponsive to immune checkpoint inhibitors (ICI) due to its profoundly immunosuppressive tumor microenvironment.
Taiki Yamazaki, Aori Minami, Misako Hirota, Mirei Hirano, Ryota Sato, Atsuki Honma, Hideto Ueki, Toshiro Shirakawa   +7 more
wiley   +1 more source

Genome-wide identification and expression analysis of the class III peroxidase gene family in Medicago sativa. [PDF]

BMC Plant Biol
Wu J, Cheng H, Liu T, Hao Z, Ma Y, Raza A, Yang P.   +6 more
europepmc   +1 more source

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

Advanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang, Yuanyuan Chu, Ruiqian Zhao, Siyu Li, Yu Feng, Hongdan Zheng, Yunli Xie, Tong Wang, Wenyu Wen   +8 more
wiley   +1 more source

Exploring Fungal Biodegradation Pathways of 2,4-D: Enzymatic Mechanisms, Synergistic Actions, and Environmental Applications. [PDF]

ACS Omega
Barros do Nascimento AC, Nhampossa NA, Félix TP, Itabaiana I, do Nascimento RP.   +4 more
europepmc   +1 more source

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

Advanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida, Yanghao Zhong, Akiko Kumagai, William G. Dunphy, Shasha Chong   +4 more
wiley   +1 more source

Integrated Genomic and Transcriptomic Analyses Reveal a Two-Tier Adaptive Strategy for Wheat Root Salt Tolerance: Constitutive Auxin Biosynthetic Capacity and Stress-Responsive Transcriptional Repression. [PDF]

Biology (Basel)
Kim KH, Jeong JY, Kim T, Park SY, Lee BM, Kim JY.   +5 more
europepmc   +1 more source

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

THE INACTIVATION OF INVERTASE BY PEROXIDASE

Journal of Biological Chemistry, 1953
openaire   +2 more sources

Detection and characterization of a compound 1 species from the <i>c</i>-type heme enzyme cytochrome <i>c</i>'_β. [PDF]

Chem Sci
Paris JC, Nguyen J, Kim HJ, Hendrich MP.
europepmc   +1 more source

Straight vs blended applications of IAA (Indole Acetic Acid) and Boron (B) for the improvement of crop productivity in maize (Zea mays L.). [PDF]

BMC Plant Biol
Hussain K, Ghaus H, Amin R, Nawaz K, Ahlawat Y, Elhindi KM, Malik A, Bashir S, Iqbal I, Arshad N.   +9 more
europepmc   +1 more source