Results 191 to 200 of about 48,716 (304)
Solvent Channels and Electric Fields Guide Proton Delivery to the Active Site of Heme Peroxidases. [PDF]
Suardíaz R +7 more
europepmc +1 more source
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source
Changes in the enzyme profile of the white-rot fungus Bjerkandera adusta in co-culture with the brown-rot fungus Gloeophyllum trabeum and its potential for dye decolorization. [PDF]
Arias B, Milagres AMF, Machuca A.
europepmc +1 more source
Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou +23 more
wiley +1 more source
Antioxidants: Mechanisms, Benefits, and the Importance of Extremophilic Microorganisms. [PDF]
Aladhadh M.
europepmc +1 more source
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang +12 more
wiley +1 more source
Emerging concepts of reactive oxygen species functions in plants. [PDF]
Foyer CH.
europepmc +1 more source
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang +10 more
wiley +1 more source
Genome-wide identification and alkaline stress response analysis of the class III peroxidase (PRX) gene family in Castanea mollissima. [PDF]
Liu X +10 more
europepmc +1 more source

