Results 101 to 110 of about 9,422 (217)
Specific skeletal muscle adaptations to contractile activity appear to be modulated by redox signaling, primarily through reactive oxygen species (ROS) such as hydrogen peroxide (H₂O₂).
Malcolm J. Jackson
doaj +1 more source
Peroxynitrite‐induced structural remodeling and aggregation of hemoglobin under nitroxidative stress
Abstract Peroxynitrite (PN), generated by the reaction of nitric oxide with superoxide, is a potent reactive nitrogen species (RNS) implicated in nitroxidative protein damage in cardiovascular and neurodegenerative diseases. Hemoglobin (Hb), the principal oxygen‐transport protein of erythrocytes, is a key intravascular scavenger and target of PN ...
Shaik Basha +3 more
wiley +1 more source
Edible Insect Allergens: An Emerging Food Safety Challenge
Allergic responses to edible insects arise via two main pathways: cross‐reactivity with homologous arthropod allergens and primary sensitization to edible insect proteins, both leading to IgE‐mediated immune activation. ABSTRACT Edible insects are increasingly promoted as sustainable protein sources; however, their allergenic potential remains a ...
Changqi Liu +5 more
wiley +1 more source
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry +27 more
wiley +1 more source
Anthyllis henoniana aerial parts were subjected to fractionated extraction. Methanolic fractions yielded high total phenolic and flavonoid contents with strong antiradical (anti‐DPPH) and neuroprotective (anti‐AChE) activities, whereas dichloromethane and cyclohexane fractions demonstrated potent cytotoxicity (anti‐MCF‐7, anti‐HCT‐116) and anti ...
Sabrine Jaber +3 more
wiley +1 more source
New perspectives on the physiological basis of muscle loss
Experimental Physiology, EarlyView.
Alistair J. Monteyne, Marlou L. Dirks
wiley +1 more source
We evaluated adaptation to torpor and hibernation in the genus Dromiciops by comparing it with both torpid and non‐torpid marsupials, and investigated divergent selection signals between its two species. For the ancestral node, we identified positive selection in the genes PFKFB2, LAMP3, OTX1, and RAPSN, alongside an enrichment of pathways potentially ...
Elisa Gonzalez‐Ugalde +7 more
wiley +1 more source
Microbial Oxidative Stress in Food Fermentations: A Comprehensive Review
Oxidative stress has a dual role in food fermentations: low ROS supports adaptive signaling, whereas excessive ROS causes cellular damage and process inhibition. Managing redox state as a controllable process variable can improve fermentation robustness and final food quality.
Wanrong Hu +11 more
wiley +1 more source
Phenolic‐rich extracts from five indigenous Algerian Vitis vinifera leaf cultivars were characterized by LC–MS and evaluated for antioxidant, antidiabetic, antibacterial, and molecular docking activities. The Azorith‐fereinguel cultivar showed superior bioactivity, attributed mainly to isoquercitrin, hesperidin, and rutin.
Radhia Belmanaa +6 more
wiley +1 more source
ABSTRACT Organotin (IV) compounds are known to induce apoptosis via the intrinsic mitochondrial pathway, which is a key mechanism of effective anticancer therapy. Their ability to selectively promote apoptotic cell death highlights their potential as chemotherapeutic agents. In this study, the in vitro effects of two triorganotin compounds, tributyltin
Dana Strouhalova +3 more
wiley +1 more source

