Results 101 to 110 of about 19,535 (281)

Analyses of the three 1-Cys Peroxiredoxins from Aspergillus fumigatus reveal that cytosolic Prx1 is central to H2O2 metabolism and virulence

open access: yesScientific Reports, 2018
Standing among the front defense strategies against pathogens, host phagocytic cells release various oxidants. Therefore, pathogens have to cope with stressful conditions at the site of infection.
M. C. Rocha   +11 more
semanticscholar   +1 more source

Organ‐Specific Cancer‐Associated Fibroblast Subtypes Across the Digestive System Linked to Cancer Hallmarks

open access: yesCancer Science, EarlyView.
We integrated 14 single‐cell RNA‐seq datasets and 18 bulk cohorts to define eight CAF subtypes in GI cancers. myCAF1 and myCAF2 promoted immunosuppressive, poor‐prognosis niches, whereas iCAF1 was linked to favorable prognosis and antitumor immunity.
Huaitao Wang   +7 more
wiley   +1 more source

Varicocele and testicular function

open access: yesAsian Journal of Andrology, 2015
Testicular varicocele, a dilation of the veins of the pampiniform plexus thought to increase testicular temperature via venous congestion, is commonly associated with male infertility.
Alexander W Pastuszak, Run Wang
doaj   +1 more source

Long-Term Adverse Effects of Oxidative Stress on Rat Epididymis and Spermatozoa

open access: yesAntioxidants, 2020
Oxidative stress is a common culprit of several conditions associated with male fertility. High levels of reactive oxygen species (ROS) promote impairment of sperm quality mainly by decreasing motility and increasing the levels of DNA oxidation ...
Pei You Wu   +2 more
doaj   +1 more source

Roles of peroxiredoxins in cancer, neurodegenerative diseases and inflammatory diseases

open access: yesPharmacology and Therapeutics, 2016
Peroxiredoxins (PRDXs) are antioxidant enzymes, known to catalyze peroxide reduction to balance cellular hydrogen peroxide (H2O2) levels, which are essential for cell signaling and metabolism and act as a regulator of redox signaling.
M. Park   +4 more
semanticscholar   +1 more source

The oligomeric conformation of peroxiredoxins links redox state to function

open access: yes, 2009
Barranco-Medina S, Lazaro J-J, Dietz K-J. The oligomeric conformation of peroxiredoxins links redox state to function. FEBS LETTERS. 2009;583(12):1809-1816.Protein-protein associations, i.e.
Dietz, Karl-Josef   +5 more
core   +1 more source

Effects of Common Food Additives Kappa‐, Iota‐ and Lambda‐Carrageenans on Intestinal Epithelial Cell Activation and Barrier Disruption

open access: yesClinical &Experimental Allergy, EarlyView.
Carrageenans, widely used food additives, disrupted intestinal epithelial integrity in a gut‐on‐a‐chip model. All types (κ‐, ɩ‐, λ‐) induced cytotoxicity, inflammation and tight junction (TJ) disruption, triggering TNF‐mediated immune responses. λ‐Carrageenan had the most severe effects, supporting the Epithelial Barrier Theory linking food additives ...
Na Sun   +13 more
wiley   +1 more source

Peroxiredoxins in breast carcinoma

open access: yes, 2019
Purpose: Peroxiredoxins (Prxs) are a novel group of peroxidases containing high antioxidant efficiency and some of them having also effects on cell differentiation and apoptosis.
강상원
core  

Antioxidants Special Issue: Peroxiredoxin 6 as a Unique Member of the Peroxiredoxin Family [PDF]

open access: yesAntioxidants, 2019
The peroxiredoxins, first discovered about 30 years ago, are the most recently described family of ubiquitously expressed antioxidant enzymes [...]
openaire   +3 more sources

Methods to Study Mitochondrial Metabolism and Homeostasis in Fission Yeast

open access: yes
Yeast, EarlyView.
Ferran Gómez‐Armengol   +2 more
wiley   +1 more source

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