Results 101 to 110 of about 9,422 (217)

Abstract 051 | Age-related disruption of redox-regulated signalling following contractile activity in skeletal muscle

open access: yesEuropean Journal of Translational Myology
Specific skeletal muscle adaptations to contractile activity appear to be modulated by redox signaling, primarily through reactive oxygen species (ROS) such as hydrogen peroxide (H₂O₂).
Malcolm J. Jackson
doaj   +1 more source

Peroxynitrite‐induced structural remodeling and aggregation of hemoglobin under nitroxidative stress

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Peroxynitrite (PN), generated by the reaction of nitric oxide with superoxide, is a potent reactive nitrogen species (RNS) implicated in nitroxidative protein damage in cardiovascular and neurodegenerative diseases. Hemoglobin (Hb), the principal oxygen‐transport protein of erythrocytes, is a key intravascular scavenger and target of PN ...
Shaik Basha   +3 more
wiley   +1 more source

Edible Insect Allergens: An Emerging Food Safety Challenge

open access: yesSustainable Food Proteins, Volume 4, Issue 3, September 2026.
Allergic responses to edible insects arise via two main pathways: cross‐reactivity with homologous arthropod allergens and primary sensitization to edible insect proteins, both leading to IgE‐mediated immune activation. ABSTRACT Edible insects are increasingly promoted as sustainable protein sources; however, their allergenic potential remains a ...
Changqi Liu   +5 more
wiley   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

open access: yesActa Ophthalmologica, Volume 104, Issue 6, Page 604-615, September 2026.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry   +27 more
wiley   +1 more source

Phytochemical Profiling and Biological Evaluation of Anthyllis henoniana Organs: Integrated In Vitro and Molecular Docking Insights Into Antioxidant, Anti‐Inflammatory, and Cytotoxic Potential

open access: yesChemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Anthyllis henoniana aerial parts were subjected to fractionated extraction. Methanolic fractions yielded high total phenolic and flavonoid contents with strong antiradical (anti‐DPPH) and neuroprotective (anti‐AChE) activities, whereas dichloromethane and cyclohexane fractions demonstrated potent cytotoxicity (anti‐MCF‐7, anti‐HCT‐116) and anti ...
Sabrine Jaber   +3 more
wiley   +1 more source

New perspectives on the physiological basis of muscle loss

open access: yes
Experimental Physiology, EarlyView.
Alistair J. Monteyne, Marlou L. Dirks
wiley   +1 more source

Frozen and Scorched: Genomic Signatures of Adaptive Divergence and Hibernation in the Living Fossil Dromiciops

open access: yesEcology and Evolution, Volume 16, Issue 8, August 2026.
We evaluated adaptation to torpor and hibernation in the genus Dromiciops by comparing it with both torpid and non‐torpid marsupials, and investigated divergent selection signals between its two species. For the ancestral node, we identified positive selection in the genes PFKFB2, LAMP3, OTX1, and RAPSN, alongside an enrichment of pathways potentially ...
Elisa Gonzalez‐Ugalde   +7 more
wiley   +1 more source

Microbial Oxidative Stress in Food Fermentations: A Comprehensive Review

open access: yeseFood, Volume 7, Issue 4, August 2026.
Oxidative stress has a dual role in food fermentations: low ROS supports adaptive signaling, whereas excessive ROS causes cellular damage and process inhibition. Managing redox state as a controllable process variable can improve fermentation robustness and final food quality.
Wanrong Hu   +11 more
wiley   +1 more source

New Insights Into the Phytochemical Composition and Biological Potential of Leaf Extracts From Algerian Autochthonous Vitis vinifera L.

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
Phenolic‐rich extracts from five indigenous Algerian Vitis vinifera leaf cultivars were characterized by LC–MS and evaluated for antioxidant, antidiabetic, antibacterial, and molecular docking activities. The Azorith‐fereinguel cultivar showed superior bioactivity, attributed mainly to isoquercitrin, hesperidin, and rutin.
Radhia Belmanaa   +6 more
wiley   +1 more source

Monitoring the Effect of Tributyltin Salicylate and Propionate, Retinoid X Receptor Ligands, on Heat Shock Protein Expression in MDA‐MB‐231 Cells by MALDI MS/MS

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 8, August 2026.
ABSTRACT Organotin (IV) compounds are known to induce apoptosis via the intrinsic mitochondrial pathway, which is a key mechanism of effective anticancer therapy. Their ability to selectively promote apoptotic cell death highlights their potential as chemotherapeutic agents. In this study, the in vitro effects of two triorganotin compounds, tributyltin
Dana Strouhalova   +3 more
wiley   +1 more source

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