Results 111 to 120 of about 19,535 (281)

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

open access: yesThe FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia   +7 more
wiley   +1 more source

The redox switch that regulates molecular chaperones

open access: yesBiomolecular Concepts, 2015
Modification of reactive cysteine residues plays an integral role in redox-regulated reactions. Oxidation of thiolate anions to sulphenic acid can result in disulphide bond formation, or overoxidation to sulphonic acid, representing reversible and ...
Conway Myra E., Lee Christopher
doaj   +1 more source

Differential parameters between cytosolic 2‐Cys peroxiredoxins, PRDX1 and PRDX2

open access: yesProtein Science, 2018
Peroxiredoxins are thiol‐dependent peroxidases that function in peroxide detoxification and H2O2 induced signaling. Among the six isoforms expressed in humans, PRDX1 and PRDX2 share 97% sequence similarity, 77% sequence identity including the active site,
Joaquín Dalla Rizza   +4 more
semanticscholar   +1 more source

Polyethylene Terephthalate Micro and Nanoplastics Induce Oxidative and Endoplasmic Reticulum Stress, Compromising Intestinal Epithelial Integrity and Viability

open access: yes
Allergy, EarlyView.
Sena Ardicli   +18 more
wiley   +1 more source

Transcriptomic and proteomic signatures underlying nymphal adaptation and foam production in the forage pest Mahanarva spectabilis

open access: yesInsect Molecular Biology, EarlyView.
RNA‐seq and Batelli gland proteomics of fifth‐instar Mahanarva spectabilis nymphs reveal transcripts and proteins associated with xylem feeding, foam production and environmental interaction. Functional annotation identified genes involved in osmoregulation, detoxification, chemosensation and stress responses, while proteomic analysis confirmed ...
Monique da Silva Bonjour   +8 more
wiley   +1 more source

Exploring the role of mononuclear phagocytes in the epididymis

open access: yesAsian Journal of Andrology, 2015
The onslaught of foreign antigens carried by spermatozoa into the epididymis, an organ that has not demonstrated immune privilege, a decade or more after the establishment of central immune tolerance presents a unique biological challenge.
Nicolas Da Silva, Tegan B Smith
doaj   +1 more source

Distinct roles of peroxiredoxins within the chloroplast redox-regulatory network of A. thaliana

open access: yes, 2021
Telman W. Distinct roles of peroxiredoxins within the chloroplast redox-regulatory network of A. thaliana.
Telman, Wilena
core  

Peroxiredoxin 5: Structure, Mechanism, and Function of the Mammalian Atypical 2-Cys Peroxiredoxin

open access: yesAntioxidants & Redox Signaling, 2011
Peroxiredoxin 5 (PRDX5) was the last member to be identified among the six mammalian peroxiredoxins. It is also the unique atypical 2-Cys peroxiredoxin in mammals. Like the other five members, PRDX5 is widely expressed in tissues but differs by its surprisingly large subcellular distribution.
Knoops, Bernard   +3 more
openaire   +3 more sources

Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola

open access: yesInsect Molecular Biology, EarlyView.
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez   +1 more
wiley   +1 more source

Subdivision of the bacterioferritin comigratory protein family of bacterial peroxiredoxins based on catalytic activity.

open access: yes, 2010
Peroxiredoxins are ubiquitous proteins that catalyze the reduction of hydroperoxides, thus conferring resistance to oxidative stress. Using high-resolution mass spectrometry, we recently reclassified one such peroxiredoxin, bacterioferritin comigratory ...
CL Mackay (21822083)   +7 more
core   +2 more sources

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