Results 31 to 40 of about 4,693,382 (193)

MoPex19, which is essential for maintenance of peroxisomal structure and woronin bodies, is required for metabolism and development in the rice blast fungus. [PDF]

PLoS ONE, 2014
Peroxisomes are present ubiquitously and make important contributions to cellular metabolism in eukaryotes. They play crucial roles in pathogenicity of plant fungal pathogens.
Ling Li, Jiaoyu Wang, Zhen Zhang, Yanli Wang, Maoxin Liu, Hua Jiang, Rongyao Chai, Xueqin Mao, Haiping Qiu, Fengquan Liu, Guochang Sun   +10 more
doaj   +1 more source

Peroxisomal regulation of energy homeostasis: Effect on obesity and related metabolic disorders

Molecular Metabolism, 2022
Background Peroxisomes are single membrane-bound organelles named for their role in hydrogen peroxide production and catabolism. However, their cellular functions extend well beyond reactive oxygen species (ROS) metabolism and include fatty acid ...
Brian A. Kleiboeker, Irfan J. Lodhi
semanticscholar   +1 more source

Hepatic dysfunction in peroxisomal disorders.

Biochimica et Biophysica Acta, 2016
The peroxisomal compartment in hepatocytes hosts several essential metabolic conversions. These are defective in peroxisomal disorders that are either caused by failure to import the enzymes in the organelle or by mutations in the enzymes or in ...
M. Baes, P. V. Van Veldhoven
semanticscholar   +2 more sources

Serum very long-chain fatty acids (VLCFA) levels as predictive biomarkers of diseases severity and probability of survival in peroxisomal disorders

PLoS ONE, 2020
Peroxisomal disorders (PD) are a heterogeneous group of rare diseases caused by a defect in peroxisome biogenesis or a disruption of a peroxisomal function at a single enzyme or at transporter level.
T. Stradomska, M. Syczewska, E. Jamroz, Agata Pleskaczyńska, P. Kruczek, E. Ciara, A. Tylki-Szymańska   +6 more
semanticscholar   +1 more source

Dysfunctional peroxisomal lipid metabolisms and their ocular manifestations

Frontiers in Cell and Developmental Biology, 2022
Retina is rich in lipids and dyslipidemia causes retinal dysfunction and eye diseases. In retina, lipids are not only important membrane component in cells and organelles but also fuel substrates for energy production.
Chuck T. Chen, Zhuo Shao, Zhuo Shao, Zhuo Shao, Zhongjie Fu   +4 more
doaj   +1 more source

Pmp27 Promotes Peroxisomal Proliferation [PDF]

, 1995
Peroxisomes perform many essential functions in eukaryotic cells. The weight of evidence indicates that these organelles divide by budding from preexisting peroxisomes. This process is not understood at the molecular level.
J M Goodman, Lark, Richard H.,, Krimkevich,, Y. I., Y I Krimkevich, J M Dyer, P A Marshall, Goodman, J. M., M Veenhuis, Krimkevich, Yelena I.,, Veenhuis, Marten,, Dyer, J. M., Veenhuis, M., Marshall, Pamela A.,, Goodman, Joel M.,, Lark, R. H., Dyer, John M.,, Marshall, P. A., R H Lark   +17 more
core   +2 more sources

Beyond rare disorders: A new era for peroxisomal pathophysiology.

Molecules and Cells, 2022
Metabolism is emerging as a central influencer of multiple disease states in humans. Peroxisomes are central metabolic organelles whose decreased function gives rise to severe peroxisomal diseases.
Einat Zalckvar, M. Schuldiner
semanticscholar   +1 more source

A comparative study of peroxisomal structures in Hansenula polymorpha pex mutants [PDF]

, 2007
In a recent study, we performed a systematic genome analysis for the conservation of genes involved in peroxisome biogenesis (PEX genes) in various fungi.
Koek, Anne,, Veenhuis, Marten,, Komori, Masayuki,, Komori, Masayuki, Klei, Ida J. van der,, Koek, Anne, Veenhuis, Marten, van der Klei, Ida J.; id_orcid, van der Klei, Ida J.   +8 more
core   +2 more sources

Pay32p of the Yeast Yarrowia lipolytica Is an Intraperoxisomal Component of the Matrix Protein Translocation Machinery [PDF]

, 1995
Pay mutants of the yeast Yarrowia lipolytica fail to assemble functional peroxisomes. One mutant strain, pay32-1, has abnormally small peroxisomes that are often found in clusters surrounded by membranous material.
Rachubinski, Richard A., Szilard, Rachel K., Rachubinski, Richard A.,, Titorenko, Vladimir I.,, V I Titorenko, R A Rachubinski, Titorenko, Vladimir I., Rachel K. Szilard, M Veenhuis, Veenhuis, Marten,, R K Szilard, Szilard, Rachel K.,, Richard A. Rachubinski, Marten Veenhuis, Veenhuis, Marten, Vladimir I. Titorenko   +15 more
core   +2 more sources

Cytoprotective and Antioxidants in Peroxisomal Neurodegenerative Diseases

Proceedings, 2019
Several of the peroxisomal neurodegenerative disorders are the consequence of a specific deficiency of an enzyme or a transporter involved in peroxisomal beta-oxidation of very long chain fatty acids [1,2].
Mustapha Cherkaoui-Malki, Saad Shaaban, Mounia Tahri-Joutey, Ahmed Elshobaky, Fatima-Ezzahra Saih, Dominique Vervandier-Fasseur, Claus Jacob, Boubker Nasser, Norbert Latruffe, Pierre Andreoletti   +9 more
doaj   +1 more source