Results 291 to 300 of about 310,705 (340)

Spectrum of genetic alterations in patients with peroxisome biogenesis defects in the Iranian population: a case series study. [PDF]

BMC Med Genomics
Khalilian S, Fathi M, Jamshidi S, Madannejad R, Sayad A, Ghafouri-Fard S, Miryounesi M.   +6 more
europepmc   +1 more source

PAS7 encodes a novel yeast member of the WD-40 protein family essential for import of 3-oxoacyl-CoA thiolase, a PTS2-containing protein, into peroxisomes.

, 1994
Martina Marzioch, Ralf Erdmann, Marten Veenhuis, W H Kunau   +3 more
openalex   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

Medicinal Research Reviews, EarlyView.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh, Shubham Mahajan, Sadikalmahdi Abdella, Rehan Khan, Sanjay Garg   +4 more
wiley   +1 more source

Bacterial pathogens hijack host cell peroxisomes for replication vacuole expansion and integrity. [PDF]

Sci Adv
Hossain MJ, Romanov KA, Jian J, Swaby LC, Bandyopadhyay S, Guan I, Thomas SM, Olive AJ, O'Connor TJ.   +8 more
europepmc   +1 more source

Effect of Lactobacillus plantarum Extracellular Vesicles on Lipid Metabolism in Mice Fed a High‐Fat Diet

Molecular Nutrition &Food Research, EarlyView.
Extracellular vesicles from Lactobacillus plantarum improved lipid metabolism in HFD‐fed mice by regulating hepatic genes involved in lipid synthesis and oxidation. They also alleviated intestinal dysfunction by reducing inflammation, enhancing barrier function, and modulating gut microbiota and metabolites, underscoring their therapeutic potential in ...
Shan‐Shan Xu, Chun‐Jing Yu, Meng‐Yao Qin, Yan Zhang, Jia‐Ping Jiang, Wei Liu, Yu Pan, Song Zhang, Xiao‐Yu Zhao   +8 more
wiley   +1 more source

Second-line therapies in PBC-related cirrhosis: balancing efficacy and safety. [PDF]

Hepatobiliary Surg Nutr
Rogalski P, Rogalska M.
europepmc   +1 more source

A Mediterranean Diet‐Based Food Mix Ameliorates Diabetes‐ and Obesity‐Associated Liver Alterations Through Mitochondrial and Metabolic Reprogramming

Molecular Nutrition &Food Research, EarlyView.
Metabolic syndrome (MetS)‐related conditions are key factors in liver damage. A Mediterranean lifestyle shows promise in managing MetS, though its mechanisms remain unclear. This study tested a lab‐designed food mix mimicking the 1960s Mediterranean Diet (MD) on obese and diabetic mice; it prevented hyperlipidemia and reduced oxidative liver damage ...
Giovanna Mercurio, Antonia Giacco, Antonio Dario Troise, Moira Ledbetter, Sabrina De Pascale, Nicla Scopigno, Michela Vigliotti, Matteo Mazzola, Giuseppe Riccio, Andrea Scaloni, Maria Moreno, Alberto Fiore, Federica Cioffi, Elena Silvestri   +13 more
wiley   +1 more source

Identification and Experimental Validation of Prognostic Signature and Peroxisome-Related Key Genes in Clear Cell Renal Cell Carcinoma. [PDF]

Int J Gen Med
Fan C, Li Y, Zhang W, Wang Y, Li Y, Zheng J, Yu Z, Guo Y.   +7 more
europepmc   +1 more source

Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element.

, 1994
Ngoc Vu‐Dac, Kristina Schoonjans, Bernard Laine, Jean‐Charles Fruchart, Johan Auwerx, Bart Staels   +5 more
openalex   +1 more source

Effect of Extra Virgin Olive Oil High in Bioactive Compounds on Atherosclerosis in Apoe‐Deficient Mice

Molecular Nutrition &Food Research, EarlyView.
EVOO with high content of squalene and the dialdehyde form of decarboxymethyl oleuropein aglycone in HBC consumed by mice reduced atherosclerotic foci and growth of plaques in both sexes. These findings were accompanied by decreases in APOA1, paraoxonase 1, lipoprotein oxidation, expression of CD36 in monocytes, increased differentiation of macrophages
Roberto Martínez‐Beamonte, Cristina Barranquero, Laura Soler, Tania Herrero‐Continente, Anny Carolina Rondón, Carmen Arnal, Gloria Estopañán, Roberto Lasheras, María Jesús Rodriguez‐Yoldi, Joaquín Carlos Surra, Olga Martín‐Belloso, Isabel Odriozola‐Serrano, Jesús Osada, María Ángeles Navarro   +13 more
wiley   +1 more source