Results 111 to 120 of about 1,161,477 (260)

Molecular analysis and prenatal diagnosis of peroxisome biogenesis disorders (1) Genomic stucture and identification of 11 novel mutations of the PEX6 (peroxisome assembly factor-2) gene in patients with peroxisome biogenesis disorders (2) Prenatal diagnosis of peroxisome biogenesis disorders by means of immunofluorescence staining of cultured chorionic villous cells [PDF]

, 2000
博士論文 (Doctoral dissertation)(1) Genomic stucture and identification of 11 novel mutations of the PEX6 (peroxisome assembly factor-2) gene in patients with peroxisome biogenesis disorders(2) Prenatal diagnosis of peroxisome biogenesis disorders by means ...
397137, 張, 忠義
core   +2 more sources

Peroxisomal dysfunction interferes with odontogenesis and leads to developmentally delayed teeth and defects in distinct dental cells in Pex11b-deficient mice.

PLoS ONE
Human peroxisomal biogenesis disorders of the Zellweger syndrome spectrum affect skeletal development and induce tooth malformations. Whereas several peroxisomal knockout mouse studies elucidated the pathogenesis of skeletal defects, little information ...
Claudia Colasante, Julia Jednakowski, Klaus-Peter Valerius, Xiaoling Li, Eveline Baumgart-Vogt   +4 more
doaj   +1 more source

Activation of peroxisome proliferator-activated receptor alpha in human peripheral blood mononuclear cells reveals an individual gene expression profile response [PDF]

, 2007
Peripheral blood mononuclear cells (PBMCs) are relatively easily obtainable cells in humans. Gene expression profiles of PBMCs have been shown to reflect the pathological and physiological state of a person.
Afman, Lydia A., Bouwens, M., Müller, Michael, Müller Michael, Afman, Lydia, Afman, Lydia A, Afman, L.A., Michael Müller, Bouwens Mark, Müller, M.R., Mark Bouwens, Afman Lydia A, Bouwens, Mark, Lydia A Afman   +13 more
core   +1 more source

Evolutionary Conserved and Divergent Responses to Copper Zinc Superoxide Dismutase Inhibition in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn, Fabian B. Haas, Benjamin G. Chavez, Bernd H. Dreyer, Erik V. Reiss, Anne Ziplys, Heiko Weichert, Saskia Hiltemann, José M. Ugalde, Andreas J. Meyer, John C. D'Auria, Stefan A. Rensing, Jos H. M. Schippers   +12 more
wiley   +1 more source

Cholesterol ensures ciliary polycystin-2 localization to prevent polycystic kidney disease

Life Science Alliance
Peroxisome-mediated cholesterol trafficking is essential for the ciliary localization of the polycystin complex to prevent the occurrence of polycystic kidney.
Takeshi Itabashi, Kosuke Hosoba, Tomoka Morita, Sotai Kimura, Kenji Yamaoka, Moe Hirosawa, Daigo Kobayashi, Hiroko Kishi, Kodai Kume, Hiroshi Itoh, Hideshi Kawakami, Kouichi Hashimoto, Takashi Yamamoto, Tatsuo Miyamoto   +13 more
doaj   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Metabolic reprogramming of the immune response in periodontitis

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon, Melissa Grant, Iain Chapple, Joao Paulo Steffens   +3 more
wiley   +1 more source

Palmitate Induces Mitochondrial Energy Metabolism Disorder and Cellular Damage via the PPAR Signaling Pathway in Diabetic Cardiomyopathy

Diabetes, Metabolic Syndrome and Obesity, 2022
Xianyu Zhang, Min Mao, Zhong Zuo Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of ChinaCorrespondence: Zhong Zuo, Department of Cardiology, The First Affiliated Hospital of ...
Zhang X, Mao M, Zuo Z
doaj  

Peroxisome biogenesis and positioning

, 2010
Plant peroxisomes are extremely dynamic, moving and undergoing changes of shape in response to metabolic and environmental signals. Matrix proteins are imported via one of two import pathways, depending on the targeting signal within the protein.
Baker, A, Sparkes, Imogen A, O'Leary-Steele, Catherine, Warriner, Stuart L, Warriner, SL, Baker, Alison, O'Leary-Steele, C, Brown, LA, Brown, Laura-Anne, Sparkes, IA   +9 more
core   +1 more source

A Drosophila model for the Zellweger spectrum of peroxisome biogenesis disorders [PDF]

, 2011
SUMMARY Human peroxisome biogenesis disorders are lethal genetic diseases in which abnormal peroxisome assembly compromises overall peroxisome and cellular function.
Jing Li, Fred D. Mast, Maninder K. Virk, Andrew J. Simmonds, Richard A. Rachubinski, Sarah C. Hughes   +5 more
core   +1 more source