Results 101 to 110 of about 1,161,477 (260)

Peroxisome Biogenesis and Degradation in Yeast: A Structure/Function Analysis [PDF]

, 2000
In yeast, peroxisomes are the site of specific catabolic pathways that characteristically include hydrogen peroxide producing oxidases and catalase. During the last 10 years, much progress has been made in unravelling the molecular mechanisms involved in
Veenhuis, M, Veenhuis, Marten,, Van der Klei, IJ, Salomons, Florian A.,, Klei, Ida J. van der,, Van der Klei, IJ; id_orcid, Salomons, FA   +6 more
core   +2 more sources

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Hippocampal SIRT1 signaling mediates the ameliorative effect of treadmill exercise on anxiety- and depression-like behavior in APP/PS1 mice

Frontiers in Aging Neuroscience
ObjectiveAnxiety and depression-like symptoms occur in the early stages of Alzheimer’s disease. Hippocampal Sirtuin 1 (SIRT1) signaling mediates anxiety- and depression-like behavior.
Yarong Wang, Yarong Wang, Rongxing Zhang, Yumin Jiang, Jingwen Liao, Jingwen Liao, Lianwei Mu, Lianwei Mu, Min Hu, Min Hu   +9 more
doaj   +1 more source

Brilliant Blue G, but not Fenofibrate, Treatment Reverts Hemiparkinsonian Behavior and Restores Dopamine Levels in an Animal Model of Parkinson's Disease

Cell Transplantation, 2017
Parkinson's disease (PD) is a neurodegenerative disorder, characterized by the loss of dopaminergic neurons in the substantia nigra and their projections to the striatum.
Enéas G. Ferrazoli, Héllio D.N. De Souza, Isis C. Nascimento, Ágatha Oliveira-Giacomelli, Telma T. Schwindt, Luiz R. Britto, Henning Ulrich   +6 more
doaj   +1 more source

Late onset white matter disease in peroxisome biogenesis disorder

, 2001
OBJECTIVE: To report late onset cerebral white matter disease as a distinctive phenotype in peroxisome biogenesis disorder (PBD). BACKGROUND: There is phenotypic and genetic overlap among the PBD known as Zellweger syndrome (ZS), infantile Refsum disease
Barth, P. G., Bode, H., Gootjes, J., Majoie, C. B., Wanders, R. J., Vreken, P.   +5 more
core  

Expanding the Clinical Phenotypes of Peroxisome Biogenesis Disorders: PEX11 Function in Health and Disease

, 2014
Pex11p and related proteins, collectively termed PPPs for Pex11p-type peroxisome proliferators, constitute an unusual group of proteins among the other Pex proteins.
Hartig, A., Thoms, Sven, Brocard, C., Kettelhut, Tom   +3 more
core   +1 more source

Epigenomic Cascades Across Organs in Metabolic Dysfunction–Associated Steatotic Liver Disease: New Therapeutic Horizons

Obesity Reviews, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang, Zhongyu Huang, Sanchun Tan, Fengxia Liang, Li Chen   +4 more
wiley   +1 more source

The Health Benefits of Exercise: Molecular and Cellular Mechanisms. [PDF]

MedComm (2020)
Our synthesis integrates evidence on exercise‐induced regulatory mechanisms across multiple systems (musculoskeletal, cardiovascular, nervous, metabolic and immune), cross‐system, and aging. We also discusses adaptive regulation of exercise in extreme environments, along with the prospects and challenges of multiomics and AI‐driven precision exercise ...
Ying P, Wang H, Lu X, Zhang W, Lin Z, Wang K, Li S, Chen L, Jiang M, Hamad S, Wang Y, Wu J, Ling S.   +12 more
europepmc   +2 more sources

Emerging role of the endoplasmic reticulum in peroxisome biogenesis [PDF]

, 2013
During the past few years, we have witnessed a paradigm shift in our long-standing concept of peroxisome biogenesis. Recent biochemical and morphological studies have revealed a primary role of the endoplasmic reticulum (ER) in the de novo formation of ...
Suresh Subramani, Suresh eSubramani, Gaurav eAgrawal, Gaurav Agrawal   +3 more
core   +1 more source

Single‐Cell Transcriptomics Reveals the FA9–VAP Module Regulating Fatty Acid Accumulation in Soybean Seeds

Plant Biotechnology Journal, EarlyView.
ABSTRACT As a major commercial legume crop, soybean ranks among the world's most significant sources of edible oil and plant protein. We previously identified a SEIPIN homologue (FA9) at the fatty acid 9 locus that promotes fatty acid accumulation in soybean.
Hui Li, Tianshu Li, Xiaorui Xu, Jinhang Cui, Xin Chen, Jingyi Huang, Jia Song, Cui Mu, Xinyu Hong, Chunyan Liu, Ning Wang, Xue Han, Sui Wang, Qingshan Chen, Zhaoming Qi   +14 more
wiley   +1 more source