Results 221 to 230 of about 248,501 (390)

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Luteolin Alleviates Vascular Senescence Through Retinoic Acid-Peroxisome Proliferator-Activated Receptor Signaling and Lipid Metabolism Remodeling Combined with Multi-Omics Analysis. [PDF]

Nutrients
Bai H, Jin H, Liu T, Yin Y, Wang H, Ruan S, Li Y, Wang Z.   +7 more
europepmc   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

Ibrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard, Vivian Kapio Abem, Sagor Kumar Roy   +2 more
wiley   +1 more source

GW-9662, a peroxisome proliferator-activated receptor γ (PPARγ) inhibitor, impairs early embryonic development in zebrafish. [PDF]

Comp Biochem Physiol C Toxicol Pharmacol
Sharma S, Pathirajage KS, Johnson T, Battu JR, Dasgupta S.   +4 more
europepmc   +1 more source

Rational screening of peroxisome proliferator-activated receptor-γ agonists from natural products: potential therapeutics for heart failure [PDF]

, 2016
Rui Chen, Jing Wan, Jing Song, Qian Yan, Yong Liu, Shuiming Gu   +5 more
openalex   +1 more source

Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids.

Journal of Clinical Investigation, 1997
A. Vidal-Puig, R. Considine, M. Jimenez-Linan, A. Werman, W. Pories, J. Caro, J. Flier   +6 more
semanticscholar   +1 more source

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

International Journal of Cancer, EarlyView.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

Developmental Patterns of Hepatic Peroxisome Proliferator-Activated Receptor (PPAR) Expression in Xenopus laevis and Response to Pharmaceutical Agonists During Metamorphic Climax. [PDF]

J Exp Zool A Ecol Integr Physiol
Bushong A, Hoskins TD, Scherer M, Sepúlveda MS.   +3 more
europepmc   +1 more source

Hesperetin glucuronides induce adipocyte differentiation via activation and expression of peroxisome proliferator-activated receptor-γ [PDF]

, 2014
Kanae Gamo, Hiroyuki Miyachi, Kayoko Nakamura, Nobuyasu Matsuura   +3 more
openalex   +1 more source

Mitochondrial Biogenesis Is Impaired in Osteoarthritis Chondrocytes but Reversible via Peroxisome Proliferator–Activated Receptor γ Coactivator 1α

Arthritis & Rheumatology, 2015
Yun Wang, Xianling Zhao, M. Lotz, R. Terkeltaub, R. Liu-Bryan   +4 more
semanticscholar   +1 more source