NF Erythroid 2-Related Factor 2 Peroxisome Proliferator-Activated Receptor-γ Crosstalk: Reprogramming Monocytic Myeloid-Derived Suppressor Cells in Kidney Disease. [PDF]
Imig JD.
europepmc +1 more source
Noise‐Induced Hearing Loss: From Pathological Mechanisms to Therapeutic Interventions
ABSTRACT Noise‐induced hearing loss (NIHL), a significant non‐genetic form of hearing impairment, is primarily managed through the use of hearing aids and cochlear implants. However, the fundamental pathological mechanisms underlying NIHL remain inadequately addressed.
Shiqi Huang +7 more
wiley +1 more source
Randomized Controlled Trial Evidence on Peroxisome Proliferator-Activated Receptor (PPAR) Agonists in Primary Biliary Cholangitis: A Systematic Review and Meta-Analysis. [PDF]
Dar MS +15 more
europepmc +1 more source
This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu +5 more
wiley +1 more source
Luteolin Alleviates Vascular Senescence Through Retinoic Acid-Peroxisome Proliferator-Activated Receptor Signaling and Lipid Metabolism Remodeling Combined with Multi-Omics Analysis. [PDF]
Bai H +7 more
europepmc +1 more source
Seladelpar improved itch, itch‐related sleep disturbance and measures of fatigue in patients with primary biliary cholangitis and pruritus in the Phase 3 RESPONSE trial. ABSTRACT Background Pruritus and fatigue impose a significant burden on patient quality of life in primary biliary cholangitis (PBC).
Cynthia Levy +10 more
wiley +1 more source
GW-9662, a peroxisome proliferator-activated receptor γ (PPARγ) inhibitor, impairs early embryonic development in zebrafish. [PDF]
Sharma S +4 more
europepmc +1 more source
Christoph Handschin +4 more
semanticscholar +1 more source

