Results 191 to 200 of about 250,000 (338)

Mitochondrial Biogenesis Is Impaired in Osteoarthritis Chondrocytes but Reversible via Peroxisome Proliferator–Activated Receptor γ Coactivator 1α

Arthritis & Rheumatology, 2015
Yun Wang, Xianling Zhao, M. Lotz, R. Terkeltaub, R. Liu-Bryan   +4 more
semanticscholar   +1 more source

Paraben Exposure in the General Taiwanese Population: Reference Values, Personal Care Products, and Cumulative Risk Assessment

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Parabens (parahydroxybenzoates), which are frequently used as preservatives in pharmaceuticals, foodstuffs, and personal care products, have recently attracted considerable attention due to their adverse health effects and endocrine‐disrupting properties.
Jung‐Wei Chang, Yen‐Hsuan Huang, Hsin‐Chang Chen, Vinoth Kumar Ponnusamy, Wan‐Ting Chang, Po‐Chin Huang   +5 more
wiley   +1 more source

Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids.

Journal of Clinical Investigation, 1997
A. Vidal-Puig, R. Considine, M. Jimenez-Linan, A. Werman, W. Pories, J. Caro, J. Flier   +6 more
semanticscholar   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Activation of peroxisome proliferator-activated receptor (PPAR) by pioglitazone in oral traumatic ulcers in female rats. [PDF]

Toxicol Rep
Neto RSM, Silva LVD, Araújo CL, Valente AGF, Coelho AA, Caetano CFF, Costa GAJ, Barros Silva PG, Avelar RL.   +8 more
europepmc   +1 more source

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

Proceedings of the National Academy of Sciences of the United States of America, 1993
H. Keller, C. Dreyer, J. Medin, A. Mahfoudi, K. Ozato, W. Wahli   +5 more
semanticscholar   +1 more source

Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease

Neuroprotection, EarlyView.
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García, Edgar Alvarado, Alejandro Cuevas, Laura Valverde, Eduardo Salinas, Kevin O'Hara‐Veintimilla, María Cruz Rodríguez‐Oroz, Miguel Germán Borda   +7 more
wiley   +1 more source

Modulation of peroxisome proliferator activated receptor genes and gamma glutamyl transferase in rats by high intensity interval training and livergol. [PDF]

Sci Rep
Nameni F, Kasiri A.
europepmc   +1 more source

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, EarlyView.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

The cAMP-phosphodiesterase PDE4B2 controls peroxisome proliferator-activated receptor γ expression and the initiation of adipogenesis in 3T3-L1 cells. [PDF]

Am J Physiol Endocrinol Metab
Fiedler E, Boyd A, Irelan D, Rachek LI, Abou Saleh L, Richter W.   +5 more
europepmc   +1 more source