Results 91 to 100 of about 84,481 (342)

Ciprofloxacin but not amoxicillin significantly elevated serum peroxynitrite level in patients with enteric (typhoid fever): In vitro study

open access: yesمجلة كلية الطب, 2006
Peroxynitrite is one intermediate of reactive nitrogen species with bactericidal and cylotoxic effects. Fluoroquinolones. drugs used for salmonella infections, are interacted v\ith nitrogen species and their baeterieida effect is influenced by these ...
Marwan S.M. Al-Nimer   +1 more
doaj  

Effects of plant- and animal-based-protein meals for a day on serum nitric oxide and peroxynitrite levels in healthy young men

open access: yesEndocrine Journal
Plant-based diets that replace animal-based proteins with plant-based proteins have received increased attention for cardiovascular protection. Nitric oxide (NO) plays an essential role in the maintenance of endothelial function.
Tomoko Kaneko   +8 more
doaj   +1 more source

The Interaction of Hypotaurine and Other Sulfinates with Reactive Oxygen and Nitrogen Species:A Survey of Reaction Mechanisms [PDF]

open access: yes, 2017
Considerable strides have been made in understanding the oxidative mechanisms involved in the final steps of the cysteine pathway leading to taurine.
A Baseggio Conrado   +38 more
core   +2 more sources

The role of peroxiredoxins in cancer [PDF]

open access: yes, 2017
Peroxiredoxins (PRDXs) are a ubiquitously expressed family of small (22-27 kDa) non-seleno peroxidases that catalyze the peroxide reduction of H2O2, organic hydroperoxides and peroxynitrite.
CAPALBO, CARLO   +4 more
core   +1 more source

X‐ray controlled release strategy in cancer therapy

open access: yesBMEMat, EarlyView.
A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan   +5 more
wiley   +1 more source

Hypoxia helps glioma to fight therapy [PDF]

open access: yes, 2009
Despite major improvements in the surgical management the prognosis for patients bearing malignant gliomas is still dismal. Malignant gliomas are notoriously resistant to treatment and the survival time of patients is between 3-8 years for low-grade and
Amberger-Murphy, Verena
core   +1 more source

Cell signaling and cytotoxicity by peroxynitrite. [PDF]

open access: yesEnvironmental Health Perspectives, 2002
Reactive nitrogen species are now considered to play an important role in various pathologies. Although the pathological significance of these molecules, peroxynitrite in particular, has long been attributed to their abilities to react with any component of the cells, including lipids, proteins, and DNA, a paradigm shift has recently been occurring ...
CANTONI, ORAZIO   +5 more
openaire   +3 more sources

Targeting Fluorescent Sensors to Endoplasmic Reticulum Membranes Enables Detection of Peroxynitrite During Cellular Phagocytosis.

open access: yesACS Chemical Biology, 2018
Peroxynitrite is a highly reactive oxidant derived from superoxide and nitric oxide. In normal vertebrate physiology, some phagocytes deploy this oxidant as a cytotoxin against foreign pathogens.
Kelsey E. Knewtson   +2 more
semanticscholar   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

open access: yesBMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang   +7 more
wiley   +1 more source

Anti-Oxidative, Anti-Tumor-Promoting, and<em> </em>Anti-Carcinogensis Activities of Nitroastaxanthin and Nitrolutein, the Reaction Products of Astaxanthin and Lutein with Peroxynitrite

open access: yesMarine Drugs, 2012
Astaxanthin captured peroxynitrite to form nitroastaxanthins. 15-Nitroastaxanthin was a major reaction product of astaxanthin with peroxynitrite. Here, the anti-oxidative, anti-tumor-promoting, and anti-carcinogensis activities of 15-nitroastaxanthin ...
Hideo Etoh   +4 more
doaj   +1 more source

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