Exercise redox biochemistry:conceptual, methodological and technical recommendations [PDF]
Exercise redox biochemistry is of considerable interest owing to its translational value in health and disease. However, unaddressed conceptual, methodological and technical issues complicate attempts to unravel how exercise alters redox homeostasis in ...
Bailey, Damian M.+3 more
core +6 more sources
Degradation of Hyaluronan by Peroxynitrite
Treatment of high-molecular-weight hyaluronan (HA) with peroxynitrite at neutral pH (ONOO-/ONOOH) results in altered mobility on agarose gel electrophoresis, as well as reduced limiting viscosity number. Both effects are consistent with a reduction in HA molecular weight.
Rolondo E. Vilar+3 more
openaire +3 more sources
Systemic lupus Erythematosus is an autoimmune disease of unknown aetiology affecting multiple organ system. Reactive nitrogen and oxygen species are claimed to play a role in this disease.
Shaimaa M. Mohammed+2 more
doaj +3 more sources
Formation of 2-nitrophenol from salicylaldehyde as a suitable test for low peroxynitrite fluxes
There has been some dispute regarding reaction products formed at physiological peroxynitrite fluxes in the nanomolar range with phenolic molecules, when used to predict the behavior of protein-bound aromatic amino acids like tyrosine.
Yuliya Mikhed+9 more
doaj +1 more source
Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ dysfunction in a rat model of acute sepsis [PDF]
Funding This study was funded by the Medical Research Council (Grant number G0800149). Research material from this study is not available. Acknowledgement We are very grateful to Dr Robin A.J. Smith, Department of Chemistry, University of Otago, Dunedin,
Galley, H. F.+3 more
core +1 more source
This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret+4 more
wiley +1 more source
The key role of nitric oxide in hypoxia: hypoxic vasodilation and energy supply-demand matching [PDF]
Significance: a mismatch between energy supply and demand induces tissue hypoxia with the potential to cause cell death and organ failure. Whenever arterial oxygen concentration is reduced, increases in blood flow - 'hypoxic vasodilation' - occur in an ...
Alex Dyson+23 more
core +1 more source
Light‐Harvesting Nanomaterials Based on Dyes for Energy Transfer and Amplified Biosensing
Light harvesting (LH) in plants inspires researchers to develop artificial LH nanomaterials. Here, LH nanomaterials based on organic dyes are reviewed, considering fundamental challenges on aggregation‐caused quenching, excitation energy transfer, and exciton migration length.
Andrey S. Klymchenko+2 more
wiley +1 more source
A computational model for analysis of uncoupled NO synthase on nitric oxide and superoxide interaction in microcirculation [PDF]
Nitric oxide (NO) produced by endothelial cells is a key component for blood-vessel dilation. Dilation is achieved through smooth muscle relaxation as a response to NO transport.
Kavdia, Mahendra, Richardson, William
core +2 more sources
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi+4 more
wiley +1 more source