Peroxynitrous Acid Generated In Situ from Acidified H2O2 and NaNO2. A Suitable Novel Antimicrobial Agent? [PDF]
Antibiotics, 2021 Peroxynitrite (ONOO−) and peroxynitrous acid (ONOOH) are known as short acting reactive species with nitrating and oxidative properties, which are associated with their antimicrobial effect.
Martina Balazinski +3 more
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The inflammatory oxidant peroxynitrous acid modulates the structure and function of the recombinant human V3 isoform of the extracellular matrix proteoglycan versican [PDF]
Redox Biology, 2023 Continued oxidant production during chronic inflammation generates host tissue damage, with this being associated with pathologies including atherosclerosis.
Sara M. Jørgensen +6 more
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Identification and quantification of protein nitration sites in human coronary artery smooth muscle cells in the absence and presence of peroxynitrous acid/peroxynitrite [PDF]
Redox Biology, 2023 Peroxynitrous acid/peroxynitrite (ONOOH/ONOO−) is a powerful oxidizing/nitrating system formed at sites of inflammation, which can modify biological targets, and particularly proteins.
Shuqi Xu +4 more
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Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin [PDF]
Redox Biology, 2020 Anastellin (AN), a fragment of the first type III module in fibronectin (FN), initiates formation of superfibronectin, a polymer which resembles the native cell-derived fibrillar FN found in the extracellular matrix of many tissues, but which displays ...
Jianfei He +8 more
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Oxidation of Aldehydes Used as Food Additives by Peroxynitrite [PDF]
Antioxidants, 2023 Benzaldehyde and its derivatives are used as food supplements. These substances can be used mainly as flavorings or as antioxidants. Besides, peroxynitrite, an oxidizing agent, could be formed in canned food. Both species could react between them.
Clara I. Alcolado +5 more
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Peroxynitrous Acid ‐ Where is the Hydroxyl Radical? [PDF]
IUBMB Life, 2003 AbstractPeroxynitrite is an inorganic toxin of physiological interest, formed from the diffusion‐controlled reaction of superoxide and nitrogen monoxide with a rate constant of (1.6 ± 0.3) × 1010 M ‐ 1 s ‐ 1. On the basis of three experiments we conclude that homolysis of the O‐O bond in peroxynitrous acid is unlikely: (1) the yield of nitrite from the
Reinhard Kissner +3 more
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Cross-linking and modification of fibronectin by peroxynitrous acid: Mapping and quantification of damage provides a new model for domain interactions. [PDF]
J Biol Chem, 2021 Mariotti M +3 more
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Direct Determination of the Gibbs′ Energy of Formation of Peroxynitrous Acid. [PDF]
Inorganic Chemistry, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Gábor Merényi +3 more
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Oxidation of Nitrite by Peroxynitrous Acid
The Journal of Physical Chemistry A, 2003 The kinetics of the oxidation of nitrite to nitrate by peroxynitrous acid at pH 5.2 is best described by the rate law kobs = kiso + k‘[NO2-] + k‘ ‘[NO2-]2, in which the peroxynitrous acid isomerization rate constant kiso = (1.10 ± 0.05) s-1, k‘ = (3.2 ± 0.1) M-1 s-1, and k‘ ‘ = (4.2 ± 0.3) M-2s-1, at 25 °C.
Patrick Maurer +6 more
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Mitochondria Play Essential Roles in Intracellular Protection against Oxidative Stress—Which Molecules among the ROS Generated in the Mitochondria Can Escape the Mitochondria and Contribute to Signal Activation in Cytosol? [PDF]
BiomoleculesQuestions about which reactive oxygen species (ROS) or reactive nitrogen species (RNS) can escape from the mitochondria and activate signals must be addressed.
Daisuke Masuda +19 more
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