Results 1 to 10 of about 5,835 (153)

Peroxynitrous Acid Generated In Situ from Acidified H₂O₂ and NaNO₂. A Suitable Novel Antimicrobial Agent? [PDF]

Antibiotics, 2021
Peroxynitrite (ONOO−) and peroxynitrous acid (ONOOH) are known as short acting reactive species with nitrating and oxidative properties, which are associated with their antimicrobial effect.
Martina Balazinski, Ansgar Schmidt-Bleker, Jörn Winter, Thomas von Woedtke   +3 more
doaj   +2 more sources

Oxidation of Aldehydes Used as Food Additives by Peroxynitrite [PDF]

Antioxidants, 2023
Benzaldehyde and its derivatives are used as food supplements. These substances can be used mainly as flavorings or as antioxidants. Besides, peroxynitrite, an oxidizing agent, could be formed in canned food. Both species could react between them.
Clara I. Alcolado, Luis Garcia-Rio, Juan C. Mejuto, Inmaculada Moreno, Francisco J. Poblete, Juan Tejeda   +5 more
doaj   +2 more sources

The inflammatory oxidant peroxynitrous acid modulates the structure and function of the recombinant human V3 isoform of the extracellular matrix proteoglycan versican [PDF]

Redox Biology, 2023
Continued oxidant production during chronic inflammation generates host tissue damage, with this being associated with pathologies including atherosclerosis.
Sara M. Jørgensen, Lasse G. Lorentzen, Astrid Hammer, Gerald Hoefler, Ernst Malle, Christine Y. Chuang, Michael J. Davies   +6 more
doaj   +2 more sources

Identification and quantification of protein nitration sites in human coronary artery smooth muscle cells in the absence and presence of peroxynitrous acid/peroxynitrite [PDF]

Redox Biology, 2023
Peroxynitrous acid/peroxynitrite (ONOOH/ONOO−) is a powerful oxidizing/nitrating system formed at sites of inflammation, which can modify biological targets, and particularly proteins.
Shuqi Xu, Christine Y. Chuang, Clare L. Hawkins, Per Hägglund, Michael J. Davies   +4 more
doaj   +2 more sources

Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin [PDF]

Redox Biology, 2020
Anastellin (AN), a fragment of the first type III module in fibronectin (FN), initiates formation of superfibronectin, a polymer which resembles the native cell-derived fibrillar FN found in the extracellular matrix of many tissues, but which displays ...
Jianfei He, Eva Ramos Becares, Peter Waaben Thulstrup, Luke F. Gamon, Jannik Nedergaard Pedersen, Daniel Otzen, Pontus Gourdon, Michael J. Davies, Per Hägglund   +8 more
doaj   +2 more sources

Multifunctional Fluorescent Probe for Simultaneous Detection of ATP, Cys, Hcy, and GSH: Advancing Insights into Epilepsy and Liver Injury. [PDF]

Adv Sci (Weinh)
A multifunctional fluorescent probe, BCR, is designed for the simultaneous detection of adenosine triphosphate (ATP), gluotathione (GSH), homocysteine (Hcy), and cysteine (Cys). Furthermore, probe BCR successfully visualizes changes in ATP, GSH, Hcy, and Cys levels in a PTZ‐induced epileptic zebrafish model and an APAP‐induced mouse liver injury tissue
Yu T, Li Y, Li J, Gan Y, Long Z, Deng Y, Zhang Y, Li H, Yin P, Yao S.   +9 more
europepmc   +2 more sources

Mitochondria Play Essential Roles in Intracellular Protection against Oxidative Stress—Which Molecules among the ROS Generated in the Mitochondria Can Escape the Mitochondria and Contribute to Signal Activation in Cytosol? [PDF]

Biomolecules
Questions about which reactive oxygen species (ROS) or reactive nitrogen species (RNS) can escape from the mitochondria and activate signals must be addressed.
Daisuke Masuda, Ikuo Nakanishi, Kei Ohkubo, Hiromu Ito, Ken-ichiro Matsumoto, Hiroshi Ichikawa, Moragot Chatatikun, Wiyada Kwanhian Klangbud, Manas Kotepui, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Hirofumi Matsui, Jitbanjong Tangpong, Takafumi Ichikawa, Toshihiko Ozawa, Hsiu-Chuan Yen, Daret K. St Clair, Hiroko P. Indo, Hideyuki J. Majima   +19 more
doaj   +2 more sources

Oxidative/Nitrosative Stress, Apoptosis, and Redox Signaling: Key Players in Neurodegenerative Diseases. [PDF]

J Biochem Mol Toxicol
Enzymatic and nonenzymatic antioxidant defense mechanisms are activated to counteract the detrimental effects of augmented free radicals, oxidants, and nitrogen compounds within the cell. ABSTRACT Neurodegenerative diseases are significant health concerns that have a profound impact on the quality and duration of life for millions of individuals. These
Üremiş N, Üremiş MM.
europepmc   +2 more sources

50 Years of Organoselenium Chemistry, Biochemistry and Reactivity: Mechanistic Understanding, Successful and Controversial Stories. [PDF]

Chemistry
From the stink to the stars! The reputation of organoselenium species changed drastically in the past fifty years. While at the beginning of their history they were notoriously famous for their toxicity and infernal smell, organoselenides are nowadays recognized for their fundamental role in redox biology and as green organocatalysts.
Madabeni A, Bortoli M, Nogara PA, Ribaudo G, Dalla Tiezza M, Flohé L, Rocha JBT, Orian L.   +7 more
europepmc   +2 more sources

Photodissociation of Peroxynitric Acid in the Near-IR [PDF]

The Journal of Physical Chemistry A, 2002
Temperature-dependent near-IR photodissociation spectra were obtained for several vibrational overtone transitions of peroxynitric acid (HNO4) with a tunable OPO photolysis/OH laser-induced-fluorescence system. Band-integrated photodissociation cross-sections ( ∫σdiss), determined relative to that for the 3ν1 OH stretching overtone, were measured for ...
Roehl, Coleen M., Nizkorodov, Sergey A., Zhang, Hui, Blake, Geoffrey A., Wennberg, Paul O.   +4 more
openaire   +8 more sources