Results 11 to 20 of about 1,721 (149)

H₂S Is a Potential Universal Reducing Agent for Prx6-Type Peroxiredoxins. [PDF]

Adv Sci (Weinh)
We report the identification of H2S as reducing agent for Prx6‐type peroxiredoxins. In contrast to common physiological reducing agents of other peroxiredoxins, HS− is small enough to access the active site of oxidized Prx6‐type enzymes in the fully‐folded protein conformation.
Lang L, Leiskau L, Bambach L, Deponte M.
europepmc   +2 more sources

Coupled Antibacterial Effects of Plasma-Activated Water and Pulsed Electric Field

Frontiers in Physics, 2022
In the biomedical applications of cold plasma, the dominant biological effect is most typically attributed to the reactive oxygen and nitrogen species (RONS), while the physical effect of electric fields is sometimes overlooked. Here, we investigated the
Robin Mentheour, Zdenko Machala
doaj   +1 more source

Quantification and Mechanisms of Oxidative Stress in Chronic Disease

Proceedings, 2019
There is now strong evidence that the redox environment inside cells is very different to that outside the cell, and that many extracellular environments are both more oxidizing and also subject to extensive oxidation.
Michael J. Davies
doaj   +1 more source

The Balancing of Peroxynitrite Detoxification between Ferric Heme-Proteins and CO₂: The Case of Zebrafish Nitrobindin

Antioxidants, 2022
Nitrobindins (Nbs) are all-β-barrel heme proteins and are present in prokaryotes and eukaryotes. Although their function(s) is still obscure, Nbs trap NO and inactivate peroxynitrite.
Giovanna De Simone, Andrea Coletta, Alessandra di Masi, Massimo Coletta, Paolo Ascenzi   +4 more
doaj   +1 more source

Photodissociation of Peroxynitric Acid in the Near-IR [PDF]

The Journal of Physical Chemistry A, 2002
Temperature-dependent near-IR photodissociation spectra were obtained for several vibrational overtone transitions of peroxynitric acid (HNO4) with a tunable OPO photolysis/OH laser-induced-fluorescence system. Band-integrated photodissociation cross-sections ( ∫σdiss), determined relative to that for the 3ν1 OH stretching overtone, were measured for ...
Roehl, Coleen M., Nizkorodov, Sergey A., Zhang, Hui, Blake, Geoffrey A., Wennberg, Paul O.   +4 more
openaire   +3 more sources

Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization

Redox Biology, 2020
The precise characterization and quantification of oxidative protein damage is a significant challenge due to the low abundance, large variety, and heterogeneity of modifications.
Luke F. Gamon, Chaorui Guo, Jianfei He, Per Hägglund, Clare L. Hawkins, Michael J. Davies   +5 more
doaj   +1 more source

Degradation of 1,4-dioxane by reactive species generated during breakpoint chlorination: Proposed mechanisms and implications for water treatment and reuse

Journal of Hazardous Materials Letters, 2022
Breakpoint chlorination, an important chemical process relevant to chlorine-based advanced oxidation processes for potable reuse and to traditional water treatment, was investigated for its oxidative capacity, generation of reactive species, and ...
Samuel D. Patton, Michael C. Dodd, Haizhou Liu   +2 more
doaj   +1 more source

Identification and quantification of sites of nitration and oxidation in the key matrix protein laminin and the structural consequences of these modifications

Redox Biology, 2019
Laminin is a major protein of the basement membrane (BM), a specialized extracellular matrix (ECM) of the artery wall. The potent oxidizing and nitrating agent peroxynitrous acid (ONOOH) is formed at sites of inflammation, and data implicate ONOOH in ECM
Lasse G. Lorentzen, Christine Y. Chuang, Adelina Rogowska-Wrzesinska, Michael J. Davies   +3 more
doaj   +1 more source

Gene network analysis to determine the effect of hypoxia-associated genes on brain damages and tumorigenesis using an avian model

Journal of Genetic Engineering and Biotechnology, 2021
Background Hypoxia refers to the condition of low oxygen pressure in the atmosphere and characterization of response to hypoxia as a biological complex puzzle, is challenging.
Hamed Kharrati-Koopaee, Esmaeil Ebrahimie, Mohammad Dadpasand, Ali Niazi, Rugang Tian, Ali Esmailizadeh   +5 more
doaj   +1 more source

The stratospheric abundance of peroxynitric acid

Geophysical Research Letters, 1977
A recent re‐examination of the kinetics of the reaction of NO2 with HO2 shows this to be a three body reaction leading to the formation of peroxynitric acid (HO2NO2). The rate of formation is such that significant concentrations of HO2NO2 (not previously included in atmospheric models) are expected to form in the stratosphere.
J. P. Jesson, L. C. Glasgow, D. L. Filkin, C. Miller   +3 more
openaire   +1 more source