Results 121 to 130 of about 267,335 (315)
The Official Student Newspaper of UAS [PDF]
, 2015 Health Corner / First Friday -- Tidal Echoes -- Sweeney Todd / Whale Necropsy -- Calendar and ...
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Dynamics of a Mobile Phone Network
, 2008 The empirical study of network dynamics has been limited by the lack of longitudinal data. Here we introduce a quantitative indicator of link persistence to explore the correlations between the structure of a mobile phone network and the persistence of ...
Barabasi +27 more
core +2 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Self-Cultivation and Meaning through the Experience of Injury Rehabilitation: A Case Study of Two Female Basketball Players [PDF]
, 2011 This case study involved interviewing athletes who had sustained moderate to severe injuries about the experience of being injured and the potential for self-cultivation and meaning synthesized through recovering from an injury.
Tracey, Jill
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
THE INFLUENCE OF SOCIAL GOALS AND GENDER ON NEGOTIATION [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2016 This study presents the results of a survey that tested the influence of gender and type of goal (social vs. pecuniary) on Romanian people’s perceptions regarding perseverance in obtaining what they demanded and risk to project a negative image by ...
DACINIA CRINA PETRESCU
doaj
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Reconceptualising undergraduate entrepreneurship education at traditional South African universities
Acta Commercii, 2019 Orientation: The relatively high number of unemployed graduates in South Africa is a major cause for concern. Entrepreneurial start-ups have been heralded as the panacea to the unemployment challenge.
Manduth Ramchander
doaj +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source