Results 221 to 230 of about 983,813 (313)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The Persistence Index: Foundations of Persistence Measurement in Persistence Science

The Persistence Index provides the foundational framework through which persistence is measured within Persistence Science.   The theory formalizes the Persistence Index,   Ω = P/D   where P denotes Persistence Capacity and D denotes System Decay.   As one of the two foundational operational equations of Persistence Science,
openaire   +1 more source

Preclinical Imaging for the Translation of Innovative Nutritional Strategies: Current Applications and Future Perspectives. [PDF]

J Imaging
Yamaoka I.
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Metabolic memory in diabetic complications: evidence for persistent cellular states and limits of therapeutic reversal. [PDF]

Front Endocrinol (Lausanne)
Cai Y, He S, Zeng F, Liu C.
europepmc   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Machine learning identifies key microbial signatures for Salmonella enteritidis colonization and persistence in broiler ceca. [PDF]

Poult Sci
Poudel S, Zelaya FAC, Guzman EGG, Rahman FA, Naeem M, Adhikari Y, Manjankattil S, Pacheco W, Hauck R, Bourassa D, Macklin K.   +10 more
europepmc   +1 more source