Results 31 to 40 of about 54,259 (246)

Distributed Computation of Persistent Homology [PDF]

open access: yes, 2013
Persistent homology is a popular and powerful tool for capturing topological features of data. Advances in algorithms for computing persistent homology have reduced the computation time drastically -- as long as the algorithm does not exhaust the available memory.
Ulrich Bauer   +2 more
openaire   +3 more sources

Stable volumes for persistent homology

open access: yesJournal of Applied and Computational Topology, 2023
AbstractThis paper proposes a stable volume and a stable volume variant, referred to as a stable sub-volume, for more reliable data analysis using persistent homology. In prior research, an optimal cycle and similar ideas have been proposed to identify the homological structure corresponding to each birth-death pair in a persistence diagram. While this
openaire   +3 more sources

Computing persistent homology in Futhark

open access: yes, 2021
We present a massively parallel algorithm for computing persistent homology, a concept within the field of topological data analysis, and we implement it in the purely functional array-based language Futhark, which has an efficient compiler targeting ...
Erik von Brömssen   +2 more
core   +1 more source

The Persistent Homology of a Self-Map [PDF]

open access: yesFoundations of Computational Mathematics, 2014
The main result in this paper is the construction of an algorithm that takes a simplicial self map of a topological space and derives a persistent homology associated to the self map. The persistent homology is obtained as a tower of eigenspaces given by the homology of the chain maps induced by the self map.
Herbert Edelsbrunner   +2 more
openaire   +2 more sources

Object-oriented persistent homology [PDF]

open access: yesJournal of Computational Physics, 2016
Persistent homology provides a new approach for the topological simplification of big data via measuring the life time of intrinsic topological features in a filtration process and has found its success in scientific and engineering applications. However, such a success is essentially limited to qualitative data classification and analysis.
Bao Wang 0001, Guo-Wei Wei 0001
openaire   +3 more sources

Persistent homology across signatures.

open access: yes, 2021
Persistent homology across signatures.
Steven Latré (11478193)   +3 more
core   +1 more source

A Bayesian Framework for Persistent Homology

open access: yesSIAM Journal on Mathematics of Data Science, 2020
Persistence diagrams offer a way to summarize topological and geometric properties latent in datasets. While several methods have been developed that utilize persistence diagrams in statistical inference, a full Bayesian treatment remains absent. This paper, relying on the theory of point processes, presents a Bayesian framework for inference with ...
Vasileios Maroulas   +2 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Persistent Homology for Virtual Screening

open access: yes, 2018
Finding new medicines is one of the most important tasks of pharmaceutical companies. One of the best approaches to finding a new drug starts with answering this simple question: Given a known effective drug X, what are the top 100 molecules in our ...
Theodore L. Willke (5633319)   +5 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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